Revisiting the Mitochondrial Function and Communication in
Neurodegenerative Diseases
Nitu L. Wankhede,
Mayur B. Kale,
Mohit D. Umare
et al.
Abstract:Neurodegenerative disorders are distinguished by the progressive loss of anatomically or physiologically
relevant neural systems. Atypical mitochondrial morphology and metabolic malfunction are found in
many neurodegenerative disorders. Alteration in mitochondrial function can occur as a result of aberrant mitochondrial
DNA, altered nuclear enzymes that interact with mitochondria actively or passively, or due to unexplained
reasons. Mitochondria are intimately linked to the Endoplasmic reticulum (ER), and ER-m… Show more
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