Revisiting Omega and Veraguth's Sign

The melancholic omega as sign of clinical depression and Darwin’s description of melancholy

“…The Melancholic Omega and Veraguth's fold were recently revisited in an Indian publication (Saraf and Nath, 2019), which highlighted their importance to clinical settings. Our manuscript, likewise, adds to scientific literature and emphasizes the importance of these signs as historical memorials of biological psychiatry and Darwin's contribution to phenomenology and clinical psychiatry.…”

About the nonexistent “depressive facies” as a unitary entity

“…No se ha investigado la prevalencia de este signo o el de Omega en la población latinoamericana. Asimismo, estos signos se asocian directamente a la severidad de la depresión o específicamente a la depresión de tipo melancólico (8). Es decir, su especificidad y sensibilidad para la generalidad de los casos de depresión mayor pueden resultar muy discretas.…”