Revisiting First-Line Therapeutics and the Exploration of Theoretical Novel Neurohormonal Modulation Strategies of Hypothalamic Hamartoma-Induced Gelastic Epilepsy
Richard C Todd
Abstract:Epilepsy, and the treatments associated, involvebio-hormonal disruption, altered endocrine physiology, and maladaptive reproductive influence. All of which may impact seizure susceptibility. Gelastic seizures (GS), are often linked to hypothalamic hamartomas (HH), which are uncommon congenital abnormalities characterized by the often-pathognomonic triad of GS, early puberty, and developmental delay. This systematic review aims to revisit first-line therapeutics associated with GS, as well as the theoretical su… Show more
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