Revisit of wall‐induced lateral migration in particle electrophoresis through a straight rectangular microchannel: Effects of particle zeta potential

Liu, Zhijian; Li, Di; Saffarian, Maryam; Tzeng, Tzuen‐Rong; Song, Yongxin; Pan, Xinxiang; Xuan, Xiangchun

doi:10.1002/elps.201800198

Cited by 9 publications

(7 citation statements)

References 42 publications

(90 reference statements)

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“…Liu et al. further studied the wall‐induced electrokinetic focusing of four types of 10 µm diameter polystyrene particles from Sigma, Bangs, Thermo, and Duke, respectively, in 1 mM phosphate buffer through the same straight rectangular microchannel under varying DC electric fields (Fig. B).…”

Section: Straight Microchannels With Uniform Cross Sectionsmentioning

confidence: 99%

Recent advances in direct current electrokinetic manipulation of particles for microfluidic applications

Xuan

2019

Electrophoresis

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Microfluidic devices have been extensively used to achieve precise transport and placement of a variety of particles for numerous applications. A range of force fields have thus far been demonstrated to control the motion of particles in microchannels. Among them, electric field‐driven particle manipulation may be the most popular and versatile technique because of its general applicability and adaptability as well as the ease of operation and integration into lab‐on‐a‐chip systems. This article is aimed to review the recent advances in direct current (DC) (and as well DC‐biased alternating current) electrokinetic manipulation of particles for microfluidic applications. The electric voltages are applied through electrodes that are positioned into the distant channel‐end reservoirs for a concurrent transport of the suspending fluid and manipulation of the suspended particles. The focus of this review is upon the cross‐stream nonlinear electrokinetic motions of particles in the linear electroosmotic flow of fluids, which enable the diverse control of particle transport in microchannels via the wall‐induced electrical lift and/or the insulating structure‐induced dielectrophoretic force.

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Section: Straight Microchannels With Uniform Cross Sectionsmentioning

confidence: 99%

Recent advances in direct current electrokinetic manipulation of particles for microfluidic applications

Xuan

2019

Electrophoresis

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“…For instance, the micro-detection and therapy of bone crack by diffusiophoresis is a good demonstration as the injured or ill human tissues often release specific chemicals [5]. Indeed, although electrophoresis is still the major workhorse for now in various practical applications utilizing electrokinetic flows [6][7][8][9], diffusiophoresis is coming from behind with a fast pace, especially in the field of drug delivery with the reasons mentioned above [10][11][12][13]. In particular, many important experimental studies were reported by Shin et al recently to broaden the potential practical applications of diffusiophoresis [14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Diffusiophoresis of a highly charged soft particle normal to a conducting plane

Lee

2021

Electrophoresis

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Diffusiophoresis of a soft particle in electrolyte solutions normal to a conducting solid plane is investigated theoretically in this study, focusing on the highly charged particle in particular. A pseudo‐spectral method based on Chebyshev polynomial is adopted to solve the resultant governing electrokinetic equations. It was found, among other things, that the closer the soft particle is to the plane, the faster it moves in general, provided only the chemiphoresis component of the diffusiophoresis is involved, i.e., no diffusion potential is present. The presence of the conducting plane is found to have three effects upon the particle motion nearby: the geometric boundary confinement effect, the electrostatic mirror‐image force analog effect, and the hydrodynamic retarding effect. The enhancement of the double layer polarization by the first two effects leads to the seeming intriguing observation mentioned above. The particle always moves away from the plane in chemiphoresis. If a diffusion potential is present, however, then it is possible to drive the particle toward the plane. The results have potential applications in drug delivery.

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“…Moreover, the fluid elasticity effect was demonstrated to tune the lateral particle migration in the electro‐hydrodynamic flow of polyethylene oxide (PEO) solutions, which can be opposite or similar to that in a Newtonian fluid as the polymer concentration is varied [35–38]. In addition, the fluid shear thinning effect was found to direct particles in the electroosmotic flow of xanthan gum (XG) solution toward the microchannel walls [39], opposite to the wall‐induced centerline focusing effect in a Newtonian fluid [40].…”

Section: Introductionmentioning

confidence: 99%

Fluid rheological effects on streaming dielectrophoresis in a post‐array microchannel

et al. 2021

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Recent studies have demonstrated the strong influences of fluid rheological properties on insulator‐based dielectrophoresis (iDEP) in single‐constriction microchannels. However, it is yet to be understood how iDEP in non‐Newtonian fluids depends on the geometry of insulating structures. We report in this work an experimental study of fluid rheological effects on streaming DEP in a post‐array microchannel that presents multiple contractions and expansions. The iDEP focusing and trapping of particles in a viscoelastic polyethylene oxide solution are comparable to those in a Newtonian buffer, which is consistent with the observations in a single‐constriction microchannel. Similarly, the insignificant iDEP effects in a shear‐thinning xanthan gum solution also agree with those in the single‐constriction channel except that gel‐like structures are observed to only form in the post‐array microchannel under large DC electric fields. In contrast, the iDEP effects in both viscoelastic and shear‐thinning polyacrylamide solution are significantly weaker than in the single‐constriction channel. Moreover, instabilities occur in the electroosmotic flow and appear to be only dependent on the DC electric field. These phenomena may be associated with the dynamics of polymers as they are electrokinetically advected around and through the posts.

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Revisit of wall‐induced lateral migration in particle electrophoresis through a straight rectangular microchannel: Effects of particle zeta potential

Cited by 9 publications

References 42 publications

Recent advances in direct current electrokinetic manipulation of particles for microfluidic applications

Recent advances in direct current electrokinetic manipulation of particles for microfluidic applications

Diffusiophoresis of a highly charged soft particle normal to a conducting plane

Fluid rheological effects on streaming dielectrophoresis in a post‐array microchannel

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