The Nearctic species of Nephrocerus Zetterstedt, 1838 are revised and include two described species, N. daeckei Johnson, 1903 and N. slossonae Johnson, 1915, and four new species: N. acanthostylus spec. nov., N. atrapilus spec. nov., N. corpulentus spec. nov. and N. woodi spec. nov. A key to species is provided and diagnostic characters, including male and female genitalia, are illustrated. Nephrocerus is recorded for the Neotropical Region for the first time.