Revisión del cáncer de seno maxilar en 23 pacientes tratados con radioterapia postoperatoria

Manrique, Rubén; Deive, Leopoldo G.; Uehara, Michel A.; Manrique, Roslyn K.; Rodríguez, José Antonio García del Castillo; Santidrian, Carmelo

doi:10.1016/s0001-6519(08)73250-3

Cited by 6 publications

(6 citation statements)

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“…Tumors were predominantly T3 or T4 as observed in 351 of 379 patients (92.6%). Similar incidence has been presented from other parts of the world [ 4 , 5 , 8 , 9 ]. Sakai et al [ 3 ] reported a series of 773 patients with maxillary sinus carcinoma seen in a 22-year period between 1959 and 1979.…”

Section: Discussionsupporting

confidence: 82%

“…Because symptoms are vague and nonspecific, the majority of carcinomas are diagnosed as locally advanced disease [ 2 ]. Extension to contiguous structures including the orbit, ethmoid sinus, sphenoid sinus, nasal cavity, nasopharynx, pterygoid fossa, palate and cheek may occur and can be a potential problem in the surgical and/or radiotherapeutic management of this disease [ 2 , 9 ]. In our study, frequency of invasion was highest into the tissue underlying the skin (134 patients, 35%) followed by involvement of ethmoid sinuses (98 patients, 25.8%) and skin of the cheek (95 patients, 25%).…”

Section: Discussionmentioning

confidence: 99%

“…However, the experience with regard to the incidence and presentation in Western Europe and the United States is similar. Carcinomas of the maxillary sinus comprise nearly 80% of all cases of paranasal sinus tumors [ 6 - 9 ]. In a fairly good majority of patients, this cancer is diagnosed in advanced stages, making it difficult to determine the origin of the neoplasm [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

“…Carcinomas of the maxillary sinus comprise nearly 80% of all cases of paranasal sinus tumors [ 6 - 9 ]. In a fairly good majority of patients, this cancer is diagnosed in advanced stages, making it difficult to determine the origin of the neoplasm [ 9 ]. Although the majority of maxillary sinus carcinomas are locally advanced at diagnosis because its symptoms are nonspecific and resemble sinusitis [ 2 ], yet these tumours tend to remain localized to maxilla for a long time and during evolution they invade adjacent structures such as bone, base of the skull, facial soft tissue, oral cavity, and orbits[ 2 , 6 , 7 , 10 - 13 ].…”

Section: Introductionmentioning

confidence: 99%

“…Treatment of these tumors has included either surgery, radiation therapy, or a combination of both. Nevertheless, in more advanced stages, both surgery and radiotherapy have limitations [ 2 , 6 , 9 , 14 ]. The purpose of this article was to review our experience with maxillary sinus carcinoma and to examine the results of various approaches to treatment as given in our hospital.…”

Section: Introductionmentioning

confidence: 99%

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Results of Treatment of Squamous Cell Carcinoma of Maxillary Sinus: A 26-Year Experience

et al. 2010

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BackgroundFive-year survival in squamous cell carcinoma of maxillary antrum is low. This article examines the results of various approaches to treatment as given in our hospital in past 26 years.MethodsFrom 1979 to 2005, 379 patients with squamous cell carcinoma of maxillary antrum managed with curative intent were studied. Twenty-eight patients had T2, 237 patients had T3, and 114 had T4 tumors. The N classification was N0 in 316 patients, N1 in 21 patients, N2a in 28 patients and N2b in 14 patients. Treatment to the primary site comprised of surgery (Sx) and radiation therapy (RT) in 284 patients, RT alone in 57 patients and chemotherapy (CTx) with radiotherapy in 38 patients.ResultsThere was a difference in survival between patients who underwent Sx with RT compared with patients who received RT alone or CTx with RT. The most common pattern of recurrence was in the primary site, 187 (49.3%) patients. Local control at 3 and 5 years was 71% and 63.8% respectively in Sx with RT, 31.6% and 28% respectively in RT, and 28.9% and 26% in CTx with RT group.ConclusionsThe type of treatment to the primary site is an important determinant of survival and local control. Surgery with radiation is a better treatment option.

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Section: Discussionsupporting

confidence: 82%