Revisión de los carcinomas de senos paranasales

Gras-Cabrerizo, Juan R.; García, Adolfo Sarandeses; Gilia, Joan Ramón Montserrat i; Dotu, César Orús

doi:10.1016/s0001-6519(07)74925-7

Cited by 11 publications

(8 citation statements)

References 88 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The epidemiologic, clinical, and pathologic variables studied in 27 patients are similar to those described in previous series published in the literature. 2,4,6,7 The overall survival rate of patients in our series was 28% after 5 years, similar to the Western published series. 4,6,7 However, a Japanese study reported a 5-year survival of 67% in T4 tumors.…”

Section: Discussionsupporting

confidence: 89%

“…A wide variety of histologic types of tumors originates in this anatomic area, mostly epithelial (>75%), of which the most common is SCC, accounting for 80% to 90% of all nasal tumors. [1][2][3] Sinonasal SCCs are located in a complex anatomic area, close to structures such as the eyes and brain, which is of special relevance for surgery and postoperative treatment, since mutilation and aesthetic deformities are difficult to avoid. 4 Despite improvements in the field of surgery and radiotherapy, patients with these tumors still face a very unfavorable prognosis.…”

mentioning

confidence: 99%

“…In Spain, the incidence is <1 case per 100,000 inhabitants per year, occurring predominantly among men with a mean age of presentation of 50 to 60 years. 2,5 Its most frequent origin is the nasal cavity, followed by the maxillary sinus, although these numbers are reversed in some publications. 1,3 The clinical presentation of patients with sinonasal SCC is very insidious, and tumors are often diagnosed at advanced stages.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Genomic profiling of sinonasal squamous cell carcinoma

López¹,

Llorente²,

García‐Inclán³

et al. 2011

Head & Neck

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 89%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Genomic profiling of sinonasal squamous cell carcinoma

López¹,

Llorente²,

García‐Inclán³

et al. 2011

Head & Neck

View full text Add to dashboard Cite

show abstract

“…El tratamiento de estas patologías difiere según el tipo de neoplasia, pero se basa en el tratamiento quirúrgico, quimioterapia y radioterapia (Khademi et al;Gras Cabrerizo et al, 2007).…”

Section: Discussionunclassified

Cáncer de Senos Paranasales y sus Manifestaciones Orales: Reporte de Dos Casos Clínicos

Hernández

et al. 2013

Int. J. Odontostomat.

View full text Add to dashboard Cite

RESUMEN: Los carcinomas de senos paranasales son entidades poco frecuentes y cuando se diagnostican, generalmente ya se encuentran en estados avanzados de la enfermedad, dado que el proceso neoplásico en las etapas iniciales crece invadiendo las cavidades paranasales, para luego en etapas avanzadas producir la deformación de las corticales. Dentro de las manifestaciones clínicas se pueden presentar epistaxis, obstrucción nasal, dolor en zona maxilar, dolor o movilidad dentaria. Se presentan dos casos clínicos que dentro de las primeras manifestaciones cursaron con dolor de la zona maxilar y movilidad anormal de un diente. Al momento de realizar el diagnóstico definitivo los procesos tumorales se encontraban muy avanzados, comprometiendo diversas estructuras como seno maxilar, etmoidal, esfenoidal, y piso de órbita, lo que obliga a realizar grandes resecciones de la zona maxilofacial. El rol del odontólogo en el diagnóstico de la enfermedad podría ser de gran importancia, al sospechar que un aumento de volumen del reborde, la movilidad dentaria anormal o un dolor de la zona maxilar no siempre corresponden a causas odontogénicas.PALABRAS CLAVE: cáncer de senos paranasales, carcinoma nasosinusal, neoplasias malignas. INTRODUCCIÓNLos carcinomas de senos maxilares son entidades de presentación poco frecuente, encontrándose alrededor de 0,2-0,8% de las neoplasias, un 3% de los carcinomas de cabeza y cuello, y un 80% de los casos de tumores de senos paranasales (Quitral et al., 2003;Pires de Souza et al., 2006). La mayoría de los pacientes presentan un estado avanzado de la enfermedad al momento de presentar el primer signo clínico, y cuando el tumor es de pequeño tamaño, puede ser mal diagnosticado como sinusitis crónica, pólipo nasal, obstrucción del ducto lagrimal. La tomografía computarizada (TC) y la resonancia magnética son técnicas útiles para evaluar la extensión del tumor en áreas adyacentes (Pires de Souza et al.). Aproximadamente el 85% de las neoplasias antromaxilares corresponden a carcinomas epidermoides, y un 5-15% a carcinoma adenoquístico (Pires de Souza et al.).Entre el 40-60% de los casos presentan asimetrías faciales, aumentos de volumen en la cavidad oral, y extensión del tumor a la cavidad nasal. Estas lesiones pueden invadir la órbita, seno etmoidal, alvéolos dentales y paladar, fosa pterigopalatina y mús-culos pterigoideos. A través de la fosa pterigoides, puede extenderse hacia la fisura orbitaria y senos cavernosos (Pires de Souza et al.).El objetivo de este trabajo es presentar dos casos de cáncer de senos paranasales, de diagnóstico tardío, los cuales presentaron sintomatología a nivel de la cavidad oral dentro de las primeras manifestaciones. REPORTE DE CASOSCaso Clínico 1. Mujer de 40 años de edad, proveniente de un sector rural. Acude a consultorio local por primera vez al presentar episodio de epistaxis, lugar donde se le realiza un taponamiento nasal anterior.

show abstract

“…During the last two decades, we have witnessed advan ces in various fields regarding the diagnosis and treatment of nasal tumors, with new histological classifications, surgical navigation devices and techniques, radiation and chemotherapy modalities [1]. However, prognosis remains generally poor [2].…”

Section: Introductionmentioning

confidence: 99%

Malignant tumors of the nose and paranasal sinuses: a retrospective review of a Portuguese cancer center’s experience

Castelhano

Correia

Raposo

et al. 2021

Opuholi golovy i šei

View full text Add to dashboard Cite

Introduction. Although uncommon from a population-based perspective, there is considerable morbidity and mortality associated with malignant tumors of the nose and paranasal sinuses.The objective of this study was to characterize the presentation, risk factors, management and survival of patients with these tumors treated at a single institution.Materials and methods. We retrospectively reviewed the clinical records of patients with malignancies of the nose and paranasal sinuses diagnosed between January 2010 and December 2014 at a tertiary cancer center. Univariate and multivariate analysis were performed.Results. Ninety patients were included in the study. Mean age at diagnosis was 62.8 years (range, 2–95 years) and mean follow-up was 44.5 months (range, 2–113 months). The maxillary sinus (33.3 %) and the nasal cavity (32.2 %) were the most frequent sites of origin. Squamous cell carcinoma (36.7 %), mucosal melanoma (15.6 %) and adenoid cystic carcinoma (10 %) were the most common histologic subtypes. Surgery was the primary treatment for 86.7 % of patients. Recurrence occurred in 45 patients (50 %). The overall 5‑year survival was 39.3 % and disease free-survival was 45.9 %. Survival was significantly decreased in non-smokers (p = 0.022), T3–4 tumors (p = 0.007), positive lymph nodes (p <0.001), nonepithelial tumors (p = 0.036) and positive margins (p = 0.032). Survival was not affected by surgical approach between endoscopic, open and combined approaches (p = 0.088).Conclusion. Prognosis is poor, with high recurrences and low survival, but clearly histology, location and stage-dependent. Sound oncologic principles, with complete resections and negative margins, result in a better outcome.

show abstract

Revisión de los carcinomas de senos paranasales

Cited by 11 publications

References 88 publications

Genomic profiling of sinonasal squamous cell carcinoma

Genomic profiling of sinonasal squamous cell carcinoma

Cáncer de Senos Paranasales y sus Manifestaciones Orales: Reporte de Dos Casos Clínicos

Malignant tumors of the nose and paranasal sinuses: a retrospective review of a Portuguese cancer center’s experience

Contact Info

Product

Resources

About