2002
DOI: 10.1097/00003086-200211000-00056
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Review Systemic Effects of Femoral Nailing

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Cited by 65 publications
(10 citation statements)
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“…Our preferred technique is a midshaft femoral derotational osteotomy over an antegrade intramedullary nail. Though historical literature has reported the occurrence of fat embolism syndrome in the pediatric patient and deformity correction, in our practice, by utilizing the previously reported technique of femoral venting prior to reaming, we have not experienced this complication (see Figure 12) [120][121][122][123][124][125][126][127]. Another advantage of this intramedul-…”
Section: Transverse Plane Malalignmentmentioning
confidence: 90%
“…Our preferred technique is a midshaft femoral derotational osteotomy over an antegrade intramedullary nail. Though historical literature has reported the occurrence of fat embolism syndrome in the pediatric patient and deformity correction, in our practice, by utilizing the previously reported technique of femoral venting prior to reaming, we have not experienced this complication (see Figure 12) [120][121][122][123][124][125][126][127]. Another advantage of this intramedul-…”
Section: Transverse Plane Malalignmentmentioning
confidence: 90%
“…These authors found that nailing was not related to increased mortality or morbidity in patients with femoral fractures and concomitant thoracic injuries. In a review, Giannoudis et al [ 32 ] reported that the systemic response following intramedullary nailing included the effect of embolised fat on lung tissue and an inflammatory reaction depending on polymorphism of neutrophil receptors. They believed that the effect of embolism is related to an individual patient’s response, which in turn depends on several cofactors (lung contusion, traumatic shock, pre-existing lung disease, sepsis, tissue damage, increased coagulation and altered cell cytoskeleton).…”
Section: Discussionmentioning
confidence: 99%
“…Some authors report a lung complication rate of 14.6% in femoral fractures but suggest further study is needed [ 44 ]. Additionally, a number of co-factors may be responsible for the effect that fat has on the lungs [ 32 ].…”
Section: Discussionmentioning
confidence: 99%
“…This inflammatory response involves the invasion of inflammatory cells and release of cytokines, which induce pulmonary endothelial damage and acute respiratory distress syndrome. [ 45 ]…”
Section: Special Concernsmentioning
confidence: 99%