Review—Prospects in Cancer Diagnosis: Exosome-Chip for Liquid Biopsy

Abstract

A liquid biopsy combined with an exosome chip is an important detection tool for early cancer diagnosis. Exosomes have a crucial function in the exchange of information between cells and are present in biological fluids. Exosome chips are microfluidic devices designed to isolate, capture, and analyze exosomes for analysis of patient samples. These offer on-chip detection, high-throughput analysis, and multiplex measurements. Such chips can integrate with electrochemical and optical detectors, and mass spectrometry enabling comprehensive studies of diseases. This perspective will cover the outlook on chip-based diagnostics for liquid biopsy, detection, and isolation of exosomes to support cancer diagnostics.

Review—Unveiling the Power of Deep Learning in Plant Pathology: A Review on Leaf Disease Detection

“…For instance, 4,24 used SVM method for detection of tea leaf disease by taking dataset of 150 samples and achieved 93% accuracy. Taohidul Islam used [25][26][27] naive bayes method on 60 images of rice plant and achieved 90% accuracy. Chit Su Hlaing et al 28 worked on tomato leaf disease classification using plant village dataset.…”

Tailored MXenes and graphene as efficient telemedicine platforms for personalized health wellness

“…Cancer stands as one of the foremost contributors to global mortality. 64,65 Thus, the imperative to devise novel, sophisticated, and precise approaches within the realm of cancer research has grown significantly. 65–67 These approaches target early detection and treatment, aiming to enhance diagnostic outcomes while minimizing the adverse effects of therapies.…”

Performance Comparison of Lossy Mode Resonance Refractive Index Sensors on Structures Based on Graphene and MoS2

“…[1][2][3][4] First introduced as biosensor by Nylander and Liedberg in 1982, 5 SPR biosensors have been developed in various configurations such as coupled with prism, grating, and fiber optics. 6,7 To date, this device is not only used for medical applications such as detecting glucose, 8 DNA, 9 exosomes, 10 antigen, 11 virus, 12 but has also been used in the field of food safety, 13,14 and environmental monitoring. 15 Although SPR biosensors have long been explored, this device still relies on gold as a transducer material, making cheap devices challenging to achieve.…”