Review—Progress on Carbon-Based Electrochemical Sensors for Epinephrine and Norepinephrine

Abstract

A novel electrochemical sensor was constructed by employing zirconium based metal organic framework (NH2-UiO-66) and walnut derived carbon (WC) as modified materials for the highly sensitive and selective determination of paracetamol (Para) and para-aminophenol (PAP). Characterization results of the texture properties of the NH2-UiO-66/WC nanocomposite revealed that highly dispersive MOF particles were filled in large pores of WC to form homogeneous composite. The resulting composite modified electrode showed excellent electrocatalytic ability for the target molecules and good conductivity. Under optimal experimental conditions, the obtained NH2-UiO-66/WC electrode presented excellent analytical performances for Para and PAP detection with wide linear range (1-150 μM) and low detection limits (0.17 μM for Para and 0.32 μM for PAP). Finally, the proposed method was successfully used in determination of Para and PAP contents in River water and commercial tablets with satisfactory recoveries.