Review: Practical Use of a Neurophysiological Detector and the Protocol for High-Performance Liquid Chromatography

Abstract

The main aim for discovery and development of the neurophysiological detector was detection of the production' seats and criminal use of poisons in warfare. Phosphor-organic (PO) substances with acetylcholinesterase-blocking effects are prohibited in warfare by international law (Geneva Protocol. https://www.un.org/disarmament/wmd/bio/1925-geneva-protocol/). Monitoring PO analogs with acetylcholinesterase-blocking effects and their degradation products in water and soil can provide clues to unlawful production sites and the possible use of POs in warfare. Attempts to analyze POs by derivatization have had a low ability to detect them. A neurophysiological detector (NPD)-high-performance liquid chromatography (HPLC) system was developed for specific detection with high detection ability. The first official How to cite this paper: Brondz, I. ( 2023) Review: Practical Use of a Neurophysiological Detector and the Protocol for High-