Review on vat photopolymerization additive manufacturing of bioactive ceramic bone scaffolds

Abstract

Bone defects frequently occur in clinical settings due to trauma, disease, tumors, and other causes.

Embedded bioprinted multicellular spheroids modeling pancreatic cancer bioarchitecture towards advanced drug therapy

“…14 Researchers utilized superhydrophobic surfaces to produce a core-shell hydrogel bead structure that contained tumor and stroma components, respectively, and demonstrated higher drug resistance compared to monotypic or ECM-free tumor spheroids. Beyond these, 3D bioprinting techniques, such as inkjet bioprinting, 15 extrusion bioprinting 16 and light-assisted bioprinting, 17,18 have emerged as advanced biomanufacturing technologies that allow cell-laden hydrogels to be positioned into specific structures in a programmed manner, and have been widely applied for the construction of 3D tumor models. [19][20][21] A laser-assisted bioprinting process was adopted to generate pancreas spheroid models for studying cancer initiation.…”

3D Printed Porous Zirconia Biomaterials based on Triply Periodic Minimal Surfaces Promote Osseointegration In Vitro by Regulating Osteoimmunomodulation and Osteo/Angiogenesis

“…19 For instance, Li et al successfully fabricated Al 2 O 3 TPMS supports with pore sizes of 5, 8.5, and 12 mm using VPP printing technology. 20 As a VPP technology, DLP uses digital micromirror devices to create intricate 3D objects. One notable advantage of DLP is the exceptional speed and ability to achieve high-resolution printing with meticulous detail.…”

“…In contrast to these limitations of SLS and ME techniques, VPP has emerged as the fastest-growing technology in ceramic 3D printing because of the exceptional printing accuracy with controllable parameters while ensuring high-quality surface finish . For instance, Li et al successfully fabricated Al 2 O 3 TPMS supports with pore sizes of 5, 8.5, and 12 mm using VPP printing technology …”

Biomaterials Adapted to Vat Photopolymerization in 3D Printing: Characteristics and Medical Applications

“…After designing a scaffold with various mechanical properties using conventional 3D printing methods, the inclusion of biomaterials with biological properties is possible through the development of VPP. In theory, using the right mixtures, any type of material can be transformed into a resin-like slurry printable by VPP; therefore, this technique has emerged as one of the most used in the medical field, with the greatest potential for building structures with specific biological functions [20,21].…”

“…Several reviews on the practical applications of VPP in medicine are available, presenting the technological aspects, postprocessing methods, or properties of certain materials used in a specific field, such as orthopedics or dentistry [21,[31][32][33]. However, we could not identify a comprehensive review of all of the specific properties and functionalities of the biomaterials adapted for VPP that considered the entire spectrum of their potential applications.…”