Review on the graphene based optical fiber chemical and biological sensors

Zhao, Yong; Li, Xuegang; Zhou, Xue; Zhang, Yanan

doi:10.1016/j.snb.2016.03.026

Cited by 277 publications

(110 citation statements)

References 79 publications

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“…Graphene combined SPR sensor devices have some advantages like SPR sensors but also further improve the sensitivity and optimize detection range and resonance wavelength . Optical fiber based chemical and biological senors using GO have been explained in a review by Zhao et al…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Graphene and Graphene‐Based Materials in Biomedical Science

Swetha

Manisha

Prasad

2018

Part & Part Syst Charact

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Graphene and its composite materials are very important in many disciplines of science and have been used enormously by researchers since their discovery in 2004. These are a new group of compounds, and are also wonderful model systems for quantum behavior studies. Their properties like exceptional conductivity, biocompatibility, surface area, mechanical strength, and thermal properties make them rising stars in the scientific community. Graphene and its composite compounds are utilized widely in different medical applications, for example, biosensing of biological compounds responsible for disease development, bioimaging of various cells, tissues, microorganisms, animal models, etc. In addition, they are used for enhancing and supporting the stem cell differentiation, i.e., regenerative medicine for regeneration studies of various human organs, tissue engineering in biology for the development of carrier materials, as well as in bone reformation. This review focuses on the modification procedure involved in the fabrication of graphene‐based biomaterials for various applications and recent developments in research related to graphene and graphene‐based materials in biosensing, optical sensing, gas sensing, drug, gene, protein delivery, tissue engineering, and bioimaging. In addition, the potential toxicological effects of graphene‐based biomaterials are discussed.

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Section: Biomedical Applicationsmentioning

confidence: 99%

Graphene and Graphene‐Based Materials in Biomedical Science

Swetha

Manisha

Prasad

2018

Part & Part Syst Charact

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“…[87] Consequently, temperature and GO oxidation degree should be carefully controlled in these approaches. Labelfree biosensing can be based on highly sensitive modulations in the refractive index occurring at the sensing surface, which are provoked by biomolecular recognition events.…”

Section: Go In Label-free Optical Biosensingmentioning

confidence: 99%

Graphene Oxide as an Optical Biosensing Platform: A Progress Report

2018

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IntroductionAs a 2D material, graphene oxide (GO) is a lattice-like nanostructure of hexagonal carbon rings disrupted by oxygen-containing moieties. In 2012, we discussed the outstanding physicochemical properties offered by GO and how these features can be exploited in unprecedented optical biosensing systems. [1] In fact, GO can be processed in suspension, easily complexed with biomolecules, and offers a universal highly efficient long-range photoluminescence quenching agent-among other functional properties. Furthermore, we highlighted that GO photoluminescences with energy transfer donor/acceptor molecules exposed A few years ago, crucial graphene oxide (GO) features such as the carbon/oxygen ratio, number of layers, and lateral size were scarcely investigated and, thus, their impact on the overall optical biosensing performance was almost unknown. Nowadays valuable insights about these features are well documented in the literature, whereas others remain controversial. Moreover, most of the biosensing systems based on GO were amenable to operating as colloidal suspensions. Currently, the literature reports conceptually new approaches obviating the need of GO colloidal suspensions, enabling the integration of GO onto a solid phase and leading to their application in new biosensing devices. Furthermore, most GO-based biosensing devices exploit photoluminescent signals. However, further progress is also achieved in powerful label-free optical techniques exploiting GO in biosensing, particularly using optical fibers, surface plasmon resonance, and surface enhanced Raman scattering. Herein, a critical overview on these topics is offered, highlighting the key role of the physicochemical properties of GO. New challenges and opportunities in this exciting field are also highlighted.The ORCID identification number(s) for the author(s) of this article can be found under https://doi.org/10.1002/adma.201805043.in a planar surface. [1] However, GO properties can be tailored according to its oxidation degree, lateral size, and number of layers, which was something little explored 6 years ago, and thus their impact on the overall biosensing performance was almost unknown. In addition, most of the biosensing systems based on GO were amenable to working as colloidal suspensions. Though, recent literature reports conceptually new approaches obviating the need of colloidal suspensions, which facilitates integration of GO-based biosensors into the solid phase and allows for their applications in new devices. Furthermore, the majority of the GO-based optical biosensing techniques rely on photoluminescent signals. However, further progress has also been achieved in powerful label-free optical techniques exploiting GO in biosensing. Here, we introduce a progress report on this exciting topic, underscoring challenges and opportunities in (bio)sensing accordingly. Number of LayersGO aqueous suspensions are highly stable in the form of mono layers. However, GO multilayer films can be built via

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“…Recently, research on various types of graphene oxide (GO)-based optical sensors has been reported [4,5], especially in humidity sensing [6]. GO is a two-dimensional nanomaterial that contains sp 2 and sp 3 hybridized carbon atoms along with many oxygen rich functional groups, such as epoxides and carboxylic groups, on the edges and the basal plane of a single layered graphene sheet.…”

Section: Introductionmentioning

confidence: 99%

Graphene-Oxide-Coated Long-Period Grating-Based Fiber Optic Sensor for Relative Humidity and External Refractive Index

Dissanayake

Nguyen

et al. 2018

J. Lightwave Technol.

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This is the accepted version of the paper.This version of the publication may differ from the final published version. City Research Online 1  Abstract-Graphene oxide is a very attractive material for refractive index and humidity sensing due to its unique twodimensional structure, which results in faster response times and improved sensitivity over alternative materials. In this paper, response of a graphene oxide-coated long period grating-based sensor to changes in relative humidity and external refractive index (as well as temperature to provide a correction for any changes) is reported. In fabricating the probes, an improved Hummer's method was used to synthesis the graphene oxide dispersion used as its basis, allowing coating of a functionalized long period grating by using a dip-coating technique. A consistent and stable response of the resonance dip intensity of the graphene oxide-coated long period grating was observed to the change in humidity, achieving a sensitivity of 0.15 dB / %RH with a linear correlation coefficient of 0.980 over the relative humidity range from 60%RH to 95%RH, at room temperature (25 ℃). A blue shift of the resonance band wavelength was recorded when the sensor was exposed to varying temperature conditions from 25 ℃ to 70 ℃ and the response was found to be linear, with a correlation coefficient of 0.997. When evaluating its performance as an external refractive index sensor, sensitivities of ~17dB/RIU in the lower refractive index region (1.33-1.38) and ~55 dB/RIU over the higher refractive index region (1.40-1.45) were achieved. The graphene oxide-coated long period grating sensor probe performed well, showing a good stability and repeatability over a number of test cycles in the performance evaluation carried out. Permanent repository link

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Review on the graphene based optical fiber chemical and biological sensors

Cited by 277 publications

References 79 publications

Graphene and Graphene‐Based Materials in Biomedical Science

Graphene and Graphene‐Based Materials in Biomedical Science

Graphene Oxide as an Optical Biosensing Platform: A Progress Report

Graphene-Oxide-Coated Long-Period Grating-Based Fiber Optic Sensor for Relative Humidity and External Refractive Index

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