Review on Swine Flu and Status of Swine Flu in Ethiopia

Abstract

Submit Manuscript | http://medcraveonline.com of IL-4 levels that can shift immunoglobulin production to IgE, IL-5and Eotaxinover expression lead to eosinophils migration and accumulation in lung (inflammation), IL-9 over expression leads mast cells activation, IL-13 over expression leads mucus production and obstruction of airway, IL-25 over expression leads Th2 activation, IL-33 over expression leads Th2 and basophils activation and IL-35has effect onTh2 and Th17 activation. The redundancy and pleotropism of the cytokines within this network play functional role in the pathophysiology of asthma [3][4][5]. Dynamic diseases such as asthma could enter different states based on environmental triggers and recognition of cytokines network can be more effective help to treatment and prevention approaches to asthmatic patients. Cytokines are at the core of asthma therapies. Therefore, cytokines as immune system control key, can process asthma pathophysiology and give new possibilities for asthma management. Monoclonal antibodies as strong tools to Interference of cytokines network for asthma control. References1. Athari SS, Pourpak Z, Folkerts G, Garssen J, Moin M, et al. (2016) Conjugated Alpha-Alumina nanoparticle with vasoactive intestinal peptide as a Nano-drug in treatment of allergic asthma in mice. Eur