Review on Some Bangladeshi Medicinal Plants with Anticancer Properties

Ashrafi, Sania; Masud, Mohammad Mehedi

doi:10.3329/dujps.v21i1.60401

Cited by 2 publications

(2 citation statements)

References 66 publications

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“…However, the fraction of cancer cells that did survive replicates and triggers multi-lineage differentiation in order to reassemble the tumor. The recurrent tumor is a more dangerous and resistant form of the original that changes into a more invasive form over time [ 14 , 15 ]. Once ignored, Eichhornia has recently received a lot of attention due to its usefulness in many other areas [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

Antiproliferative Action of Methanolic Petiole Extract of Eichhornia Crassipes on Human Prostate Adenocarcinoma Cell Line: An In Vitro Study

Noufal¹,

Rajesh²,

Nair³

2022

Cureus

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Background: An increasing number of people are turning to herbal medicines in their search for innovative pharmaceuticals since they are effective treatments for a wide variety of conditions and traditional herbs are rich in bioactive chemicals. In this study, we looked at whether or not a petiole extract of Eichhornia crassipes preserved in methanol inhibited the proliferation of prostate cancer (PC3) cell lines.Materials and methods: Lakes in Ezhikkara, Ernakulum, Kerala, were the source of E. crassipes. Soxhlet extraction was used to create the extract. 3-[4,5-dimethylthiazol-2-yl]2,5-diphenyltetrazolium bromide (MTT) assay was used to determine the cell viability of methanolic petiole extract at various concentrations. Mean and standard deviation was used to determine absorbance scores. Utilizing probit analysis, we determined the IC50 value. The descriptive statistics to measure the percent of viable cells along with the regression equation were calculated using SPSS.Results: It has been shown that the methanol extract significantly impacted PC3 cell lines' capacity to survive. It was also determined that increasing the medication concentration resulted in a decrease in cell viability. The percentage of living cells was measured after being exposed to methanol extracts at concentrations of 12.5 μg/ml, 25 μg/ml, 50 μg/ml, 100 μg/ml, and 200 μg/ml, and found to be 95.13, 85.88, 76.12, 64.33, and 53.62 percent, respectively. With IC50 values of 199.488 g/ml, it was shown that methanolic petiole extracts of E. crassipes are cytotoxic. Using probit analysis, we determined that the regression equation is y = -0.2051x + 90.915, with an R2 value of 0.893. Conclusion:As a result of its chemotherapeutic properties, the E. crassipes petiole extract has the potential to be employed in therapeutic applications, with the ultimate goal of bettering prostate cancer management practices and clinical results by drastically lowering cell viability. The study's results may pave the way for fresh chemotherapeutic approaches to be developed for the treatment of androgen-independent prostate cancer.

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Section: Discussionmentioning

confidence: 99%

Antiproliferative Action of Methanolic Petiole Extract of Eichhornia Crassipes on Human Prostate Adenocarcinoma Cell Line: An In Vitro Study

Noufal¹,

Rajesh²,

Nair³

2022

Cureus

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“…Abelson (1990) estimated that 75% of the global population uses MP and plant extracts for their medicinal needs [8] . It was pointed out that the dependence of more than 80% of the developing world on TM, predominantly plants, for Primary Health Care [9,10] .…”

Section: Introductionmentioning

confidence: 99%

Knowledge, attitude and perception on medicinal plants and traditional medicines in Bangladesh: A cross-sectional study

Islam,

Rashid

2023

J. Med. Plants Stud.

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Medicinal Plants (MP) and Traditional Medicine (TM) have long been practised in Bangladesh. The descriptive type of cross-sectional survey study has conducted to evaluate the KAP on MP and TM in Bangladesh with a sample size of 2535. A face-to-face interview questionnaire has been used for data collection in 8 clusters in Bangladesh. Both descriptive and inferential statistics have been used for data analysis with a level of significance set at < .05 and < .001. The research found the Mean ± SD age 39.07±12.119 years, followed by 87.6% Muslim, 78.8% married, 28.8% up to primary level education, 27% occupation was housewife, 43.3% monthly income was 10,000-20,000 BDT, and 41.1% respondents perceived health status was good. The research also found that 28.5% age group 18-25 years, 39.2% age group 36-65 years, 46.7% of males, and 20.9% of females of the respondents had opined that MP is effective in the treatment of illness. Out of all 19.3% age group 18-35 years, 30.1% age group 36-65 years, 33.1% of male, and 16.8% of female respondents had also opined that TM is effective in the treatment of illness. As a whole 22.7% age group 18-35 years, 32.6% age group 36-65 years, 36.5% of males, and 18.8% of female respondents believed that TM is well accepted by the community in Bangladesh. In conclusion, the research will bring to the fore the importance of the Traditional Health Care System and expand knowledge on the current debates on the efficacy, safety, and reliability of MP and TM as well as its possible mainstreaming into modern health care.

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Review on Some Bangladeshi Medicinal Plants with Anticancer Properties

Cited by 2 publications

References 66 publications

Antiproliferative Action of Methanolic Petiole Extract of Eichhornia Crassipes on Human Prostate Adenocarcinoma Cell Line: An In Vitro Study

Antiproliferative Action of Methanolic Petiole Extract of Eichhornia Crassipes on Human Prostate Adenocarcinoma Cell Line: An In Vitro Study

Knowledge, attitude and perception on medicinal plants and traditional medicines in Bangladesh: A cross-sectional study

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