In order to investigate the effects of different process parameters on the surface integrity of TC4 specimens and the effect of ultrasonic-assisted rolling strengthening on the enhancement of microstructure and mechanical properties of TC4 specimens, this paper uses TC4 titanium alloy specimens as the test object for ultrasonic-assisted rolling strengthening test. The results show that increasing the spindle speed within a certain range can improve the surface morphology of the specimen, reduce the surface roughness and average pro le height, and improve the surface hardness and residual stress. The reach also nds that USRP can re ne the surface grain of TC4 and introduce the grain re nement layer and work hardening layer with the same thickness on the surface of the specimen, and the hardness decreases gradually with the increase of depth. After USRP, the surface elastic modulus of the specimen is increased from 96.98 GPa to 112.96 GPa, and the corrosion resistance has also been greatly improved, with corrosion rate reduced by about 95%.