Review on Nanoemulsion: Preparation and Evaluation

Abstract

Nanoemulsion considers a novel drug delivery system that permits controlled or sustained drug release. It is a dispersion consisting of a surfactant, oil, and clear aqueous phase, kinetically, or thermodynamically stable with droplet diameter 10-100nm. Nanoemulsion applied to increase the solubility and bioavailability of lipophilic drugs; they have many advantages for drug delivery. There are many methods for Nanoemulsion preparation like High –energy emulsification method, Spontaneous Nanoemulsion, Phase inversion temperature (PIT). It applied for many routes of delivery, thus providing a promising effect for many fields such as cosmetics, therapeutic, and biotechnology.

Optimization and Physical Characterization of Quercetin Nanoemulgel Formula as an Antibacterial Agent

“…Nanoemulgel consists of oil, water, surfactants, and basis gel [13]. The oil selection used in nanoemulsion formulation is an important factor that the drug will incorporate as a droplet in the oil phase dispersed in the aqueous phase [14]. The oils phase component will help to achieve maximum drug loading in the nanoemulsion system [15].…”

Development of nanocarriers for the encapsulation of cannabinoids and other bioactive compounds

“…Thus, in the present thesis, the HLB value of the surfactant mixture Tween 80/Labrasol/Maisine was calculated using the aforementioned equation and was determined equal to 11 which is a value capable of producing O/W NEs [462]. An attempt was made to use the hydrophilic T80 and the lipophilic lecithin as a mixture of surfactants for the preparation of stable biocompatible systems since the latter is widely used as a biocompatible and biodegradable emulsifier in various pharmaceutical, food and cosmetic products [70,77,463].…”