Review on nano-drugs

Liu, Yong; Niu, Tian-Shui; Zhang, Long; Yang, Jianshe

doi:10.4236/ns.2010.21006

Cited by 26 publications

(17 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, at present, the basic theory of nanotechnology applied in medicine and the preparation of nano-drugs are still incomplete, especially the safety of nano-drugs has many problems remain to be explored in depth. Therefore, the research in the field of nanotechnology applied in pharmaceutical industry has a great deal of work needs to be done, but the superior capability that nano-drugs owns indicates a very wide range of applications in the clinical disease treatment [85]. Because Nano-drug carriers have high targeting, favorable sustained, controlled release capability and superior cell penetration ability, it can improve efficacy of drugs and reduce side effects.…”

Section: Discussionmentioning

confidence: 97%

Research and Application of Targeting Nano-Drugs

Liu¹

2011

Nano BioMed ENG

View full text Add to dashboard Cite

Nano-drug, a new type drug, is rapidly developing with nanotechnologies in biology and medicine field. The development of nano-drug s will cause the revolution of the diagnosis and treatment. Because Nano-drug carriers have high targeting, favorable sustained, controlled release capability and superior cell penetration ability, it can improve efficacy of drugs and reduce side effects. The role of the object from the target organ, target cell to the most advanced structure in the target cells. The three levels method of targeted therapy all could complete with nanotechnology. Nano-targeting drugs can be divided into passive targeting and active targeting. Current research focuses on the development of functionalized capsules for specific targeting of cancer or immune cells, and on controlling their release properties and targeting functionalities to develop new nano-drugs.

show abstract

Section: Discussionmentioning

confidence: 97%

Research and Application of Targeting Nano-Drugs

Liu¹

2011

Nano BioMed ENG

View full text Add to dashboard Cite

show abstract

“…An example is the recently FDA-approved "solvent-free formulation of paclitaxel for the treatment of metastatic breast cancer that utilises 130-nanometer albumin-bound (nab™) technology (Abraxane ® ; nab-paclitaxel) to circumvent the requirement for solvents" [19]. An interesting approach to underscore the various requirements for a nanoparticulated drug (or "nanodrug") strategy is presented by Y. Liu [20]. The author distinguishes between active and passively targeted nanodrugs, whereby the passive targeting to tissues or organs is due to the enhanced permeability of barriers and thus offers nanoparticles and nanodrugs a more accessible route to reach the targeted area.…”

Section: Nanoformulations As "Re-inventions"mentioning

confidence: 98%

Nanotechnology in medicine: European research and its implications

Hofmann-Amtenbrink¹,

Hofmann

Hool³

et al. 2014

Swiss Med Wkly

View full text Add to dashboard Cite

In this study, we explore and discuss nanoparticles and nanoscale materials and their use in medicine (nanomedicine) and pharmaceutics (nanopharmaceutics). The study is aimed at shedding light on this highly multidisciplinary research field and at examining the influence of research funding, industrial applications, and legal and regulatory frameworks on the research in this field, a clear understanding of which is essential to efficiently support the translation of research findings into industrial and clinical applications and to enable access to a larger society.

show abstract

“…The basic theory of nano-technology applied in medicine and the preparation of nano-drugs are still incomplete, especially the safety of nano-medicines has many problems remain to be explored in depth. Therefore, the research in the field of nano-technology applied in medicine has a great deal of work needs to be done, but the superior capability that nano-drugs owns indicates a very wide range of applications in the clinical disease treatment [53].…”

Section: Solid Lipid Nanoparticles In Pulmonary Deliverymentioning

confidence: 99%

Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity

Das¹,

Chatterjee²

2017

NANO

View full text Add to dashboard Cite

Abstract:Ongoing through all the applications of nano medicines through various sources, it has been understand that preparation of polymeric nanoparticle, liposomes, Dendrimers, Solid Lipid Nanoparticle (SLN) and polymeric micelles is useful for Drug delivery system. Also, helpful to repairs the DNA and treatment of many diseases by increase rate of toxin elimination. The nano medicines in various way initiate the proper biotransformation in livers and also give rise to effective pharmacodynamics profiles. It has been discovered that many nano molecules can be converted into picomolecular medicinal dust (pMMD) entities on lowering the molecular weight, reducing the bond length and shortening the molecular length. This (pMMD) is basically useful in respiratory system treatment, Skin targeted penetration and ophthalmic disorders ramification to ensure hypothetical probability to facilitate Pico-molecular dust involvement as medicinal propeller. Because, it acquires the finest position to receptors less than nano receptors, nano enzymes, nano amino acids chain/polymers, nano pores, nano-microelements, DNA and other nano bio-molecules etc., where nano molecular modules are not effectives. The pico dust will acquires its position into the more specified pico-receptors where nano molecules cannot penetrate or lodge. Pico medicine spray could be implicated superficially over the skin surface at high pressure. So, that it get penetrate upto the subcutaneous and intradermal skin layers with 100% inoculation easily. In ophthalmic preparation, the pico-molecular drugs spray will help to open the drainage area stimulating the receptor on the iris edge corner for dilation of path openings and constriction of circular muscles of eye to create pressure for fluid ejaculation.

show abstract

Review on nano-drugs

Cited by 26 publications

References 35 publications

Research and Application of Targeting Nano-Drugs

Research and Application of Targeting Nano-Drugs

Nanotechnology in medicine: European research and its implications

Hypothetical Formulation to Propel Pico-molecular Medicinal Dust: Application to Total Elevation of Therapeutic Efficiency Compare to Nano Entity

Contact Info

Product

Resources

About