“…Once the DDKG is constructed any machine learning approach for link prediction can be used for predicting probable drugs. The network feature extraction method used here is based on random walks, which can be replaced with other local or global graph similarity based indices such as common neighbors, Jaccard index, Sorensen index, preferential attachment, Adamic-Adar index, resource allocation index, hub promoted index, Leicht-Holme-Newman index, parameter dependent index, local affinity structure index, individual attraction index, mutual information index, functional similarity weight, and local neighbors link index, Katz index, and page rank ( Fire et al, 2011 ; Mutlu et al, 2020 ). In this case, we found random walk and preferential attachment to give better results than the other features.…”