Review on Hydrogel-based pH Sensors and Microsensors

Richter, Andreas; Paschew, Georgi; Klatt, Stephan; Lienig, Jens; Arndt, Karl‐Friedrich; Adler, Hans-Jürgen P.

doi:10.3390/s8010561

Cited by 675 publications

(527 citation statements)

References 88 publications

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“…This results in low charge density and the content of mobile counter ions within the beads which leading to gel shrinking [33]. Even though the beads strength was decreased after SGF exposure, the beads were still intact and the values of beads strength are comparatively high to protect the protein from being released into the gastric region.…”

Section: Beads Strength Analysismentioning

confidence: 97%

Development of Alginate–Gum Arabic Beads for Targeted Delivery of Protein

Mohamed¹,

Mustafa²,

Fitrianto³

et al. 2017

J Biomol Res Ther

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Controlled release beads were prepared by using the combination of alginate and gum Arabic through ionotropic gelation method. Bovine serum albumin was used as model protein for in vitro assessments. The effect of amount of sodium alginate and gum Arabic as the factor affecting protein encapsulation efficiency and protein release were optimized and analyzed by using RSM-FCCD. It was observed that protein encapsulation efficiency was increased and protein release was decreased with the increase of both of the amount of sodium alginate and gum Arabic, used as polymer blend. The optimized beads showed high encapsulation efficiency (87.5 ± 3.65%) with suitable protein release (100% protein release after almost 4 hrs). The swelling of beads were highly influenced by pH of dissolution medium. These beads were also characterized by FT-IR spectroscopy, SEM and TA for protein-excipients interaction, beads surface morphology and beads strength, respectively. These calcium alginate/gum Arabic beads have good potential to be used as delivery vehicle for protein drugs.

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Section: Beads Strength Analysismentioning

confidence: 97%

Development of Alginate–Gum Arabic Beads for Targeted Delivery of Protein

Mohamed¹,

Mustafa²,

Fitrianto³

et al. 2017

J Biomol Res Ther

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“…[8][9][10][11][12][13] Because the degree of charge dissociation in polyelectrolytes is dependent on the types of ion-pairs, the physical properties of polyelectrolyte hydrogels such as conductivity, elasticity and swelling ratio are affected by counterions as well as external stimuli. [14][15][16][17] Recently, there have been increasing research efforts of combining hydrogels with other functional materials to extend their potential applications.…”

Section: Doi: 101002/adma201103767mentioning

confidence: 99%

Photoresponsive Block Copolymer Photonic Gels with Widely Tunable Photosensitivity by Counter‐Ions

Ahn¹,

Kim²,

Hyon³

et al. 2012

Advanced Materials

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“…[1][2][3][4] This distinctive character leads to the wide applications of the polyelectrolyte gel in various technologies, such as in drug delivery, 5,6 disposable diapers, 7 microsensors, 8 adaptive liquid microlenses, 9 medicine. 10 Therefore, volume transition of polyelectrolyte gel is still being widely studied today, [11][12][13][14][15][16] more than three decades after Tanaka's pioneering work.…”

Section: Introductionmentioning

confidence: 99%

Volume phase transition of polyelectrolyte gels: Effects of ionic size

Zhang

Tang

et al. 2014

The Journal of Chemical Physics

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Although the volume transition of the polyelectrolyte gel has been studied for decades, little research on the effects of size of the mobile ions has been conducted. In the present paper, Tanaka's classical theory of polyelectrolyte gel is extended to the cases of mobile ions of finite volume. In the salt free limit, the theoretical results show that the discontinuous volume transition of the polyelectrolyte gel will become a continuous one with an increase of the counterionic size. An increase in salt concentration can also make the polyelectrolyte gel in poor solvent collapse. Poorer solvent is needed to trigger the salt-induced collapse in polyelectrolyte gel with larger mobile ions than that with smaller ones. The effects of ionic size on the critical points and phase diagram of the volume transition are also discussed. The theoretical results suggest that the swelling behavior of polyelectrolyte gel might be tuned with salt of different volumes.

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Review on Hydrogel-based pH Sensors and Microsensors

Cited by 675 publications

References 88 publications

Development of Alginate–Gum Arabic Beads for Targeted Delivery of Protein

Development of Alginate–Gum Arabic Beads for Targeted Delivery of Protein

Photoresponsive Block Copolymer Photonic Gels with Widely Tunable Photosensitivity by Counter‐Ions

Volume phase transition of polyelectrolyte gels: Effects of ionic size

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