Review on antioxidants and evaluation procedures

Kumar, Suresh; Sharma, Sunil; Vasudeva, Neeru

doi:10.1007/s11655-017-2414-z

Cited by 37 publications

(28 citation statements)

References 49 publications

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“…Both T1DM and T2DM present as a highly inflammatory and oxidative pathology, presenting a direct relation to cardiovascular events. In nondrug therapy, the use of antioxidants and phenolic compounds shows positive effects on redox action and has a protective effect on the heart tissue and prevents damage to it [76][77][78]. In the present study, both resistance training and supplementation and their combination demonstrated protective effects against the damage caused by reactive species to the cardiac tissue in T1DM.…”

Section: Discussionsupporting

confidence: 59%

Effects of resistance training and turmeric supplementation on reactive species marker stress in diabetic rats

Júnior

Aidar

Santos

et al. 2020

BMC Sports Sci Med Rehabil

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Background: Type 1 diabetes mellitus (T1DM) is a metabolic disease characterized by hyperglycemia and excessive generation of reactive oxygen species caused by autoimmune destruction of beta-cells in the pancreas. Among the antioxidant compounds, Curcuma longa (CL) has potential antioxidant effects and may improve hyperglycemia in uncontrolled T1DM/TD1, as well as prevent its complications (higher costs for the maintenance of health per patient, functional disability, cardiovascular disease, and metabolic damage). In addition to the use of compounds to attenuate the effects triggered by diabetes, physical exercise is also essential for glycemic control and the maintenance of skeletal muscles. Our objective is to evaluate the effects of CL supplementation associated with moderate-to high-intensity resistance training on the parameters of body weight recovery, glycemic control, reactive species markers, and tissue damage in rats with T1DM/TD1. Methods: Forty male 3-month-old Wistar rats (200-250 g) with alloxan-induced T1DM were divided into 4 groups (n = 7-10): sedentary diabetics (DC); diabetic rats that underwent a 4-week resistance training protocol (TD); CLsupplemented diabetic rats (200 mg/kg body weight, 3x a week) (SD); and supplemented diabetic rats under the same conditions as above and submitted to training (TSD). Body weight, blood glucose, and the following biochemical markers were analyzed: lipid profile, aspartate aminotransferase (AST), alanine aminotransferase (ALT), uric acid, creatine kinase (CK), lactate dehydrogenase (LDH), and thiobarbituric acid reactive substances (TBARS). Results: Compared to the DC group, the TD group showed body weight gain (↑7.99%, p = 0.0153) and attenuated glycemia (↓23.14%, p = 0.0008) and total cholesterol (↓31.72%, p ≤ 0.0041) associated with diminished reactive species markers in pancreatic (↓45.53%, p < 0.0001) and cardiac tissues (↓51.85%, p < 0.0001). In addition, compared to DC, TSD promoted body weight recovery (↑15.44%, p ≤ 0.0001); attenuated glycemia (↓42.40%, p ≤ 0.0001), triglycerides (↓39.96%, p ≤ 0.001), and total cholesterol (↓28.61%, p ≤ 0.05); and attenuated the reactive species markers in the serum (↓26.92%, p ≤ 0.01), pancreas (↓46.22%, p ≤ 0.0001), cardiac (↓55.33%, p ≤ 0.001), and skeletal muscle (↓42.27%, p ≤ 0.001) tissues caused by T1DM.

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Section: Discussionsupporting

confidence: 59%

Effects of resistance training and turmeric supplementation on reactive species marker stress in diabetic rats

Júnior

Aidar

Santos

et al. 2020

BMC Sports Sci Med Rehabil

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“…It can be observed that the main phenolic compounds that are present in maqui berries are anthocyanins, unlike many other berries that have less anthocyanin content in comparison with the total phenolic compounds. This high anthocyanin's content greatly contributes to their superior antioxidant capacity [7].…”

Section: Optimal Conditionsmentioning

confidence: 99%

Assessment of Ultrasound Assisted Extraction as an Alternative Method for the Extraction of Anthocyanins and Total Phenolic Compounds from Maqui Berries (Aristotelia chilensis (Mol.) Stuntz)

et al. 2019

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Research interest regarding maqui (Aristotelia chilensis) has increased over the last years due to its potential health benefits as one of the most antioxidant-rich berries. Ultrasound-assisted extraction (UAE) is an advanced green, fast, and ecological extraction technique for the production of high quality extracts from natural products, so it has been proposed in this work as an ideal alternative extraction technique for obtaining extracts of high bioactivity from maqui berries. In order to determine the optimal conditions, the extraction variables (percentage of methanol, pH, temperature, ratio “sample mass/volume of solvent”, amplitude, and cycle) were analyzed by a Box-Behnken design, in conjunction with the response surface method. The statistical analysis revealed that the temperature and the percentage of methanol were the most influential variables on the extraction of the total phenolic compounds and total anthocyanins, respectively. The optimal extraction time was determined at 15 min for total phenolic compounds, while it was only 5 min for anthocyanins. The developed methods showed a high precision level with a coefficient of variation of less than 5%. Finally, the new methods were successfully applied to several real samples. Subsequently, the results were compared to those that were obtained in previous experiments by means of microwave assisted extraction (MAE). Similar extraction yields were obtained for phenolic compounds under optimized conditions. However, UAE proved to be slightly more efficient than MAE in the extraction of anthocyanins.

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“…Sunflower is characterized by anti‐inflammatory activity. The seeds of sunflowers are known to be rich in vitamin E and magnesium that serve as an excellent source of fat‐soluble antioxidant to the body (Kumar, Sharma, & Vasudeva, 2017). The antioxidant properties displayed by vitamin E neutralize the free radicals that may cause damage to the fat‐containing structures and molecules, such as cholesterol, brain cells, and cell membranes (Nowicka & Kruk, 2017).…”

Section: Nutritional Attributes and Health Importance Of Sunflowermentioning

confidence: 99%

Oilseed crop sunflower (Helianthus annuus) as a source of food: Nutritional and health benefits

Adeleke

Babalola

2020

Food Science & Nutrition

235

114

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The use of biofertilizers in developing environmentally friendly agriculture as an alternative to chemical‐based fertilizers in enhancing food production is promising in sustainable agriculture for the improvement in the yield of some commercial crops such as sunflowers and other oilseed crops in terms of quality and quantity. Sunflower is an important oilseed crop native to South America and currently cultivated throughout the world. Generally, the sunflower is considered important based on its nutritional and medicinal value. Due to its beneficial health effects, sunflower has been recognized as functional foods or nutraceutical, although not yet fully harnessed. Sunflower contains mineral elements and phytochemicals such as dietary fiber, manganese, vitamins, tocopherols, phytosterols, triterpene glycosides, α‐tocopherol, glutathione reductase, flavonoids, phenolic acids, carotenoids, peptides, chlorogenic acid, caffeic acid, alkaloids, tannins, and saponins; and these compounds contribute to their functional and nutraceutical development. The extract from sunflower is known to be a potential source of antimicrobial, anti‐inflammatory, antitumor, and antioxidants agents that protect human cells against harmful reactive oxygen molecules and pathogenic microorganisms. Also, the pharmacological survey on sunflower had revealed its curative power to different kinds of diseases. The health benefits of sunflower include blood pressure and diabetic control, skin protection, and lowering cholesterol and other functions. This review is written with appropriate referencing to previously published work and provides updated information regarding the new method of organic farming for sunflower production, nutritional and health benefits, and its by‐products as human diet and livestock feed. Also, the constraints of sunflower production are elucidated.

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Review on antioxidants and evaluation procedures

Cited by 37 publications

References 49 publications

Effects of resistance training and turmeric supplementation on reactive species marker stress in diabetic rats

Effects of resistance training and turmeric supplementation on reactive species marker stress in diabetic rats

Assessment of Ultrasound Assisted Extraction as an Alternative Method for the Extraction of Anthocyanins and Total Phenolic Compounds from Maqui Berries (Aristotelia chilensis (Mol.) Stuntz)

Oilseed crop sunflower (Helianthus annuus) as a source of food: Nutritional and health benefits

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