Review on Adaptation between Biomaterials Function of Chitosan and Its Structure

Abstract

Chitosan is a kind of amino polysaccharide biopolymer with good film-forming, biocompatibility, biodegradability, bacteriostasis and nontoxic, obtained from the deacetylation of chitin, which contains abundant active amino and hydroxyl groups. With creative properties, functions and various applications especially in the biomedical field, chitosan is mainly used as pharmaceutical membrane, gel, microsphere (microcapsule), nanoparticle, drug and gene delivery, etc. This minireview provides an overview on the structure and properties of chitosan, the applications of chitosan biomaterials is introduced, and its research and development in the biomedical field are prospected.

Eco‐friendly and non‐toxic lysozyme immobilised on chitosan bacteriostatic agent for strawberry and fresh Tremella fuciformis preservation

“…The high molecular weight of CS leads to poor solubility, and the molecules easily form intermolecular and intramolecular hydrogen bonds, resulting in high viscosity. Therefore, CS is not easily functionalised, which limits its application scope and greatly reduces its commercial application value (Zargar et al., 2015; Li & Wu, 2019).…”

“…Chitosan (CS) is a natural alkaline polysaccharide and a deacetylated derivative of chitin (Cheung et al., 2015). It has excellent properties such as non‐toxic, antibacterial, biodegradable and biocompatible (Li & Wu, 2019). It is abundant in nature and is extensively utilised in such areas as medicine, biomaterials, tissue engineering, food and nutrition (Casadidio et al., 2019; Kumara et al., 2021; Rosales et al., 2021).…”

Synthesis and Bioactivities of Marine Pyran-Isoindolone Derivatives as Potential Antithrombotic Agents

“…At present, the discovery of most drugs originates from chemical modifications of natural products [ 24 , 25 , 26 , 27 , 28 , 29 ]. Thus, chemists are devoted to synthesizing various new compounds using diverse natural products as substrates.…”

Novel Bioactive Polyketides Isolated from Marine Actinomycetes: An Update Review from 2013 to 2019

“…Marine‐based actinomycetes had attracted great attentions in recent years. More than 70 % of earth's surface is covered by oceans and seas, which provided the ‘natural incubator’ for the origin of life, hence the biodiversity in the marine ecosystems ( e. g ., deep sea floor, coral reefs) is much higher than that in tropical rainforests [7–10] . Marine‐derived rare actinomycetes are rich sources of chemicals, secondary metabolites and new drugs because of their special natural surroundings with seawater and marine sediments [11,12] .…”