2018
DOI: 10.1007/s40279-018-1014-1
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Review of WADA Prohibited Substances: Limited Evidence for Performance-Enhancing Effects

Abstract: The World Anti-Doping Agency is responsible for maintaining a Prohibited List that describes the use of substances and methods that are prohibited for athletes. The list currently contains 23 substance classes, and an important reason for the existence of this list is to prevent unfair competition due to pharmacologically enhanced performance. The aim of this review was to give an overview of the available evidence for performance enhancement of these substance classes. We searched the scientific literature th… Show more

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Cited by 71 publications
(79 citation statements)
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References 122 publications
(128 reference statements)
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“…As is well-known, three criteria are used of which at least two have to be met: 1) enhancing, or having the potential to enhance, performance; 2) posing an actual or potential health risk; and 3) being contrary to the 'spirit of sport'. Apart from its catch-all approach due to the inclusion of 'the spirit of sport', it is clear that for many substances on the List there is no good evidence that they enhance performance or cause harm (Heuberger & Cohen, 2019). The List contains substances for which dangerousness can be considered acceptable or even absent, even though the adage 'the dose makes the poison' remains correct (even water can be deadly when taken in excess).…”
Section: Escalationmentioning
confidence: 99%
“…As is well-known, three criteria are used of which at least two have to be met: 1) enhancing, or having the potential to enhance, performance; 2) posing an actual or potential health risk; and 3) being contrary to the 'spirit of sport'. Apart from its catch-all approach due to the inclusion of 'the spirit of sport', it is clear that for many substances on the List there is no good evidence that they enhance performance or cause harm (Heuberger & Cohen, 2019). The List contains substances for which dangerousness can be considered acceptable or even absent, even though the adage 'the dose makes the poison' remains correct (even water can be deadly when taken in excess).…”
Section: Escalationmentioning
confidence: 99%
“…This also translates into higher exercise potential [25]. However, the use of calcium channel inhibitors is prohibited in sports and included in the WADA (World Anti-Doping Agency) World List of Prohibited Substances [26]. Due to increased heart function (with an increase in heart rate and blood pressure), as well as the contraction of coronary vessels and coronary congestion, ischemia and myocardial infarctions may occur.…”
Section: Calciummentioning
confidence: 99%
“…Bu ajanlar, yalnızca aerosol veya inhale olarak ve hekimin yazılı olarak izin verdiği sporcular tarafından kullanılabilir. 35…”
Section: Korti̇kosteroi̇dlerunclassified