Review of titania nanotubes: Fabrication and cellular response

Tan, Ai Wen; Pingguan‐Murphy, Belinda; Ahmad, Roslina; Akbar, Sheikh A.

doi:10.1016/j.ceramint.2012.03.002

Cited by 223 publications

(145 citation statements)

References 109 publications

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“…Previous works demonstrated immobilized protein activity [33], enhanced protein adsorption [34] and cell behavior [35,36] on various nanostructured coatings.…”

Section: Introductionmentioning

confidence: 99%

Enhanced protein adsorption and cellular adhesion using transparent titanate nanotube thin films made by a simple and inexpensive room temperature process: Application to optical biochips

Nádor

Orgován

Fried

et al. 2014

Colloids and Surfaces B: Biointerfaces

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Please cite this article in press as: J. Nador, et al., Enhanced protein adsorption and cellular adhesion using transparent titanate nanotube thin films made by a simple and inexpensive room temperature process: Application to optical biochips, Colloids Surf. a b s t r a c tA new type of titanate nanotube (TNT) coating is investigated for exploitation in biosensor applications. The TNT layers were prepared from stable but additive-free sols without applying any binding compounds. The simple, fast spin-coating process was carried out at room temperature, and resulted in well-formed films around 10 nm thick. The films are highly transparent as expected from their nanostructure and may, therefore, be useful as coatings for surface-sensitive optical biosensors to enhance the specific surface area. In addition, these novel coatings could be applied to medical implant surfaces to control cellular adhesion. Their morphology and structure was characterized by spectroscopic ellipsometry (SE) and atomic force microscopy (AFM), and their chemical state by X-ray photoelectron spectroscopy (XPS). For quantitative surface adhesion studies, the films were prepared on optical waveguides. The coated waveguides were shown to still guide light; thus, their sensing capability remains. Protein adsorption and cell adhesion studies on the titanate nanotube films and on smooth control surfaces revealed that the nanostructured titanate enhanced the adsorption of albumin; furthermore, the coatings considerably enhanced the adhesion of living mammalian cells (human embryonic kidney and preosteoblast).

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“…Previous works demonstrated immobilized protein activity [33], enhanced protein adsorption [34] and cell behavior [35,36] on various nanostructured coatings.…”

Section: Introductionmentioning

confidence: 99%

Enhanced protein adsorption and cellular adhesion using transparent titanate nanotube thin films made by a simple and inexpensive room temperature process: Application to optical biochips

Nádor

Orgován

Fried

et al. 2014

Colloids and Surfaces B: Biointerfaces

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“…Additionally, materials with well-ordered nanostructure are of considerable interest for application in molecular filtration, drug delivery and tissue engineering [6][7][8]. The broad application of TiO 2 nanostructures is mainly due to the attractive nano-scale architecture offering large surface area and a high structural order.…”

Section: Introductionmentioning

confidence: 99%

TiO2 Nanotubes on Ti Dental Implant. Part 1: Formation and Aging in Hank’s Solution

Monetta

Acquesta

Carangelo

et al. 2017

Metals

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Self-organized TiO 2 nanotube layer has been formed on titanium screws with complex geometry, which are used as dental implants. TiO 2 nanotubes film was grown by potentiostatic anodizing in H 3 PO 4 and HF aqueous solution. During anodizing, the titanium screws were mounted on a rotating apparatus to produce a uniform structure both on the peaks and on the valleys of the threads. X-ray diffraction (XRD), Scanning electron microscopy (SEM), Energy dispersive X-ray (EDX) and electrochemical characterization were used to evaluate the layer, chemical composition and electrochemical properties of the samples. Aging in Hank's solution of both untreated and nanotubes covered screw, showed that: (i) samples are covered by an amorphous oxide layer, (ii) the nanotubes increases the corrosion resistance of the implant, and (iii) the presence of the nanotubes catalyses the formation of chemical compounds containing Ca and P.

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“…Recent studies indicates that osteoblast adheres better to surface of the implant with micro-scaled structures. However, those methods fabricating the micro scaled structures or increasing roughness on the surface results in the topography Most of nanostructures studied to date for cell adhesion have been nanotubes and nanowires [12]. As a structure that provides sufficient space to transfer fluid such as medium and also allow the control of the size, pitch and other factors for improved understanding, we decide that the nanowire is a proper platform to conduct our studies for the interaction between nanostructures and cells.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of TiO₂Nanowires Using Vapor-Liquid-Solid Process for the Osseointegration

Yun¹,

Kang²,

Yun³

et al. 2013

Journal of the Korean Vacuum Society

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In order to improve osseointegration for biomedical implants, it is crucial to understand the interactions between nanostructured surfaces and cells. In this study, TiO 2 nanowires were prepared via Vapor-Liquid-Solid (VLS) process with Sn as a metal catalyst in the tube furnace. Nanowires were grown with N 2 heat treatment with their size controlled by the agglomeration of Sn layers in various thicknesses. MC3T3-E1 (pre-osteoblast) were cultured on the TiO 2 nanowires for a week. Preliminary results of the cell culture showed that the cells adhere well on the TiO 2 nanowires.

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Review of titania nanotubes: Fabrication and cellular response

Cited by 223 publications

References 109 publications

Enhanced protein adsorption and cellular adhesion using transparent titanate nanotube thin films made by a simple and inexpensive room temperature process: Application to optical biochips

Enhanced protein adsorption and cellular adhesion using transparent titanate nanotube thin films made by a simple and inexpensive room temperature process: Application to optical biochips

TiO2 Nanotubes on Ti Dental Implant. Part 1: Formation and Aging in Hank’s Solution

Fabrication of TiO₂Nanowires Using Vapor-Liquid-Solid Process for the Osseointegration

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Review of titania nanotubes: Fabrication and cellular response

Cited by 223 publications

References 109 publications

Enhanced protein adsorption and cellular adhesion using transparent titanate nanotube thin films made by a simple and inexpensive room temperature process: Application to optical biochips

Enhanced protein adsorption and cellular adhesion using transparent titanate nanotube thin films made by a simple and inexpensive room temperature process: Application to optical biochips

TiO2 Nanotubes on Ti Dental Implant. Part 1: Formation and Aging in Hank’s Solution

Fabrication of TiO2Nanowires Using Vapor-Liquid-Solid Process for the Osseointegration

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Fabrication of TiO₂Nanowires Using Vapor-Liquid-Solid Process for the Osseointegration