Review of the antioxidant potential of African medicinal and food plants.

Atawodi, Sunday E.; Olowoniyi, Olufunsho D.; Adejo, Godwin O.; Liman, Mubarak Labaran; Dubey, Nawal Kishore

doi:10.1079/9781780642666.0034

Cited by 58 publications

(75 citation statements)

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“…Spices and herbs are recognized as sources of natural antioxidants that can protect man from oxidetive stress and thus play an important role in the chemoprevention against diseases that have their etiology and pathophysiology in reactive oxygen species (Atawodi, 2005;Rizwan et al, 2012;Vauzour et al, 2010). Thus, it has been recommended that adequate intake of antioxidant through the consumption of antioxidant rich foods can prevent the development of oxidative stress (Lako et al, 2008;Atawodi, 2012;Nisar et al, 2012).…”

Section: Introductionmentioning

confidence: 99%

In vivo antioxidant and hepatoprotective effects of methanolic extract of dioclea reflexa seed in rats following acute or chronic liver injury

Iliemene

Atawodi

2014

Bangladesh J Pharmacol

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Section: Introductionmentioning

confidence: 99%

In vivo antioxidant and hepatoprotective effects of methanolic extract of dioclea reflexa seed in rats following acute or chronic liver injury

Iliemene

Atawodi

2014

Bangladesh J Pharmacol

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“…All over the world, Republic of Angola is recognized for its remarkable plants biodiversity, which can be explored in a rational way for humankind benefits. Several species from the Angolan flora, tradi-tionally selected for medicinal uses, have been the target of current investigations searching for therapeutically effective drugs with antioxidant, antimicrobial, and antifungal properties (Nema et al, 2012;Kennedy and Wightrman, 2011;Silva et al, 2011;Lulekal et al, 2008;Atawodi, 2005).…”

Section: Introductionmentioning

confidence: 99%

Angolan Cymbopogon citratus used for therapeutic benefits: Nutritional composition and influence of solvents in phytochemicals content and antioxidant activity of leaf extracts

Soares

Alves

Pires

et al. 2013

Food and Chemical Toxicology

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A B S T R A C TFolk medicine is a relevant and effective part of indigenous healthcare systems which are, in practice, totally dependent on traditional healers. An outstanding coincidence between indigenous medicinal plant uses and scientifically proved pharmacological properties of several phytochemicals has been observed along the years.This work focused on the leaves of a medicinal plant traditionally used for therapeutic benefits (Ango-lan Cymbopogon citratus), in order to evaluate their nutritional value. The bioactive phytochemical com-position and antioxidant activity of leaf extracts prepared with different solvents (water, methanol and ethanol) were also evaluated.The plant leaves contained rv60% of carbohydrates, protein (rv20%), fat (rv5%), ash (rv4%) and moisture (rv9%). The phytochemicals screening revealed the presence of tannins, flavonoids, and terpenoids in all extracts. Methanolic extracts also contained alkaloids and steroids. Several methods were used to eval-uate total antioxidant capacity of the different extracts (DPPH . , NO . , and H2O2 scavenging assays, reducing power, and FRAP). Ethanolic extracts presented a significantly higher antioxidant activity (p < 0.05) except for FRAP, in which the best results were achieved by the aqueous extracts. Methanolic extracts showed the lowest radical scavenging activities for both DPPH . and NO . radicals.

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“…Both plants have a long history of use in folk medicine in African (Hamzah et al, 2013). These plants are recognized as sources of natural antioxidants that can protect against oxidative stress and thus play an important role in chemoprevention of diseases that have their aetiology and pathophysiology in reactive oxygen species [ROS] (Atawodi, 2005;Odukoya et al, 2001). …”

Section: Graded Fresh Leave Extracts Of Vernoniaamygdalina and Ocimummentioning

confidence: 99%

In vivo evaluation of graded fresh leave extracts of vernoniaamygdalina and ocimumgratissimum on some oxidative stress indicators in rats

Iyawe

Azih

2015

Biomed Res Ther

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Abstract-Background: Vernoniaamygdalina and Ocimumgratissimumare widely used plants in the tropics. The leaves of these plants are popularly acclaimed to have medicinal values, with scarce information on the effect of graded extracts in mediating oxidative stress. The interest on these leaves derives from the need to have an insight to the possible effect of thesegraded leaves extracts may have on oxidative stress. Objectives: The objective of the study was to examine the effect of graded extracts of Vernoniaamygdalina and Ocimumgratissimum leaves specifically on free radical inhibition, reducing power and lipid peroxidation in rat liver and kidneys. Methods: The leave samples were collected and air dried, homogenized and sieved to obtain particle sizes of ≤ 0.250mm. Aqueous and methanolic extracts of samples were obtained and used to assay for total alkaloid and phenolic contents, free radical scavenging activity, reducing power and the extent of lipid peroxidationin liver and kidneys were determined, using standard analytical assays. Results: Phenolic contents of both leave extracts were higher in aqueous medium vernoniaamygdalina (0.85 ± 0.07mgGAE/g) and Ocimumgratissimum (1.59 ± 0.13mgGAE/g). The alkaloid contents of the leaves were higher in methanolic extracts, with Ocimumgratissimum highest (0.96 ± 0.04μg/g) and vernoniaamygdalina (0.38 ± 0.01μg/g). The reducing power of these leaves increased with increasing extract concentrations. Ocimumgratissimum had the highest reducing power in both methanolic (3.00 O.D) and aqueous (2.82 O.D) medium in comparison with respective butylatedhydroxytoluene (BHT) (2.49 O.D) and ascorbic acid (2.16 O.D) controls. The ability to scavenge free radicals increased with increasing extract concentrations in both leaves with highest percentages in aqueous extracts.Ocimumgratissimum(95.90%) and vernoniaamygdalina(98.80%) compared to control (100%).The leave extracts of both plants significantly (p<0.05) increased lipid peroxidations in liver and kidneys of rats. Conclusion: Fresh leaves of Ocimumgratissimumand vernoniaamygdalinahave shown potentials to be valuable in reducing powers and free radical quenching.

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Review of the antioxidant potential of African medicinal and food plants.

Abstract: This chapter focuses on the antioxidant potential of African medicinal and food plants, their chemical constituents and their other medicinal properties.

Cited by 58 publications

References 0 publications

<i>In vivo</i> antioxidant and hepatoprotective effects of methanolic extract of <i>dioclea reflexa</i> seed in rats following acute or chronic liver injury

<i>In vivo</i> antioxidant and hepatoprotective effects of methanolic extract of <i>dioclea reflexa</i> seed in rats following acute or chronic liver injury

Angolan Cymbopogon citratus used for therapeutic benefits: Nutritional composition and influence of solvents in phytochemicals content and antioxidant activity of leaf extracts

In vivo evaluation of graded fresh leave extracts of vernoniaamygdalina and ocimumgratissimum on some oxidative stress indicators in rats

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