Review of Modern Techniques in Detecting Port-wine Stain Response to Laser Therapy

Le, Khanh‐Van T.; Shahidullah, Hossain; Frieden, Ilona J.

doi:10.1046/j.1524-4725.1999.08166.x

Cited by 35 publications

(28 citation statements)

References 26 publications

(109 reference statements)

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“…4 Although flashlamp-pumped pulsed dye laser (PDL) treatments are widely considered the treatment of choice for PWS, fewer than 20% of patients experience complete lightening using this method, whereas 20% to 30% are considered "poor responders". [5][6][7] It has been proposed that one reason for inadequate clinical results is that the laser parameters used are virtually identical for all PWS patients despite the commercial availability of laser systems with user-specific settings. 8,9 In order that laser treatment may be optimized on an individual patient basis, the practitioner must be aware of the vascular architecture constituting each lesion, including the number, distribution and sizes of affected vessels.…”

Section: Introductionmentioning

confidence: 99%

“…Perceived color may be influenced by a number of factors such as ambient lighting conditions, colors surrounding the subject, eye adaptation prior to viewing and viewing geometry. 7,11 Although photographic images have been applied to determine the efficacy of laser treatment for PWS, great care must be taken to minimize the effects of variations in patient positioning, camera sensitivity and lighting during acquisition, and the quality of printing or visual display of the image. 12,13 To confound this further, communication of perceived color is difficult as, for example, most PWS skin may correctly be described as 'red' in color.…”

Section: Introductionmentioning

confidence: 99%

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Simulating light transport through skin for color prediction of port wine stain lesions: a review

2012

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Abstract. A survey of the literature is presented regarding the simulation of port wine stain (PWS) skin color. Knowledge of PWS features, such as the depths and diameters of affected vessels, is essential for informing laser treatment. These may be determined through the inverse application of a skin model. The techniques which have been applied to achieve this are analyzed in detail. Radiative transfer (RT) is found to be the preferred method of simulation. By far the most common approximations to RT are the diffusion approximations, which have been applied successfully in the past and Monte Carlo techniques, which are now the methods of choice. As the requirements for improvement of laser treatment on an individual basis continues, the needs for further work towards accurate estimations of individual optical coefficients and robust, flexible simulation techniques are identified.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Simulating light transport through skin for color prediction of port wine stain lesions: a review

2012

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“…The radius of the disk filter was 10 pixels. The final image maintains only highfrequency spatial information by removing global contouring caused by facial geometry, (3) where I(x, y) is a morphologically enhanced image; I B (x, y) and B(x, y) are the original image and the blurred image processed with the spatial low-frequency pass filter, respectively. For quantitative analysis of wrinkles, the "shape factor" (SF) algorithm based on an object's perimeter and area was applied to I(x, y).…”

Section: Ppcismentioning

confidence: 99%

“…3 The EI and MI images can be utilized to objectively evaluate vascular and pigmented skin lesions, respectively. Higher index values indicate the skin lesions containing greater concentrations of blood and melanin, (4) (5) where R and G indicate normalized red and green channel images, respectively.…”

Section: Cpcismentioning

confidence: 99%

Multimodal facial color imaging modality for objective analysis of skin lesions

2008

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We introduce a multimodal facial color imaging modality that provides a conventional color image, parallel and cross-polarization color images, and a fluorescent color image. We characterize the imaging modality and describe the image analysis methods for objective evaluation of skin lesions. The parallel and cross-polarization color images are useful for the analysis of skin texture, pigmentation, and vascularity. The polarization image, which is derived from parallel and crosspolarization color images, provides morphological information of superficial skin lesions. The fluorescent color image is useful for the evaluation of skin chromophores excited by UV-A radiation. In order to demonstrate the validity of the new imaging modality in dermatology, sample images were obtained from subjects with various skin disorders and image analysis methods were applied for objective evaluation of those lesions. In conclusion, we are confident that the imaging modality and analysis methods should be useful tools to simultaneously evaluate various skin lesions in dermatology.

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“…Although, skin colour measurements are the most established and widely used technique for the objective assessment of PWS skin [5][6][7], to date this method has not been used to extract such information. In this paper, a new Monte Carlo simulation is presented which demonstrates the capability of using skin colour measurements to predict the vessel parameters of an individual PWS lesion.…”

Section: Introductionmentioning

confidence: 99%

A new Monte Carlo program for simulating light transport through Port Wine Stain skin

2013

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A new Monte Carlo programme is presented for simulating light transport through clinically normal skin and skin that has Port Wine Stains (PWS) vessels. The program consists of an eight layer mathematical skin model constructed from optical coefficients described previously.A simulation including diffuse illumination at the surface and subsequent light transport through the model is carried out using a Radiative Transfer Theory (RTT) ray-tracing technique. Total reflectance values over 39 wavelengths are scored by the addition of simulated light returning to the surface within a specified region and surface reflections (calculated using Fresnel's equations). These reflectance values are compared to measurements from individual participants and characteristics of the model are adjusted until adequate agreement is produced between simulated and measured skin reflectance curves.The absorption and scattering coefficients of the epidermis are adjusted through changes in the simulated concentrations and mean diameters of epidermal melanosomes to reproduce non-lesional skin colour. Pseudo-cylindrical horizontal vessels are added to the skin model and their simulated mean depths, diameters and number densities are adjusted to reproduce measured PWS skin colour.Accurate reproductions of colour measurement data are produced by the program, resulting in realistic predictions of melanin and PWS blood vessel parameters. Using a modest personal computer, the simulation currently requires an average of five and a half days to complete.

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Review of Modern Techniques in Detecting Port-wine Stain Response to Laser Therapy

Abstract: While many instruments are available, these techniques are limited by cost, small test size area, and/or inconclusive correlation with clinical response. A number of experimental techniques may circumvent many of the problems inherent in currently-available commercial technologies.

Cited by 35 publications

References 26 publications

Simulating light transport through skin for color prediction of port wine stain lesions: a review

Simulating light transport through skin for color prediction of port wine stain lesions: a review

Multimodal facial color imaging modality for objective analysis of skin lesions

A new Monte Carlo program for simulating light transport through Port Wine Stain skin

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