“…For instance, the partition coefficient (K d ) and mass transfer coefficient (i.e., first-order mass transfer coefficient) could not be generalized (e.g., Stockmann et al, 2017;Swami et al, 2018) because their values are extremely varied (often by order of magnitudes) at the field-scale measurements depending both on the matrix hydraulic properties (e.g., surface area, matrix porosity, permeability) and on the fracture/conduit characteristics (Howroyd & Novakowski, 2021;Lehmann et al, 2022;Maloszewski & Zuber, 1993;Zhou et al, 2007). Similarly, the values for reactive transport parameters could also be misleading particularly when they are scaled up or extrapolated, because of the oversimplification of the multifaceted processes that are varied both by chemical heterogeneities in the matrix and local/global groundwater chemistry (e.g., Howroyd & Novakowski, 2021;Jiang et al, 2023;Katz et al,1998;Kaufmann et al, 2014;Mohammadi et al, 2021;Maqueda et al, 2023, among many others). For this reason, a realistic definition of the reactive transport parameters is strictly limited by the well-defined karstic sites or site-specific applications (i.e., single-well push-pull test) (e.g., Hillebrand et al, 2012aHillebrand et al, , 2012bHillebrand et al, , 2015Priebe et al, 2022;Schiperski et al, 2016;Tran et al, 2020Tran et al, , 2021.…”