Review of evidence for the use of steroids in orthognathic surgery

Chegini, Soudeh; Dhariwal, Daljit

doi:10.1016/j.bjoms.2010.11.019

Cited by 44 publications

(44 citation statements)

References 24 publications

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“…A reduction in swelling around the wound should enhance the local circulation, which might paradoxically improve wound healing. 39 The risk of systemic toxicity will also be reduced with submucosal administration.…”

Section: Discussionmentioning

confidence: 99%

A Randomized Clinical Trial of the Effects of Submucosal Dexamethasone After Surgery for Mandibular Fractures

Dongol¹,

Jaisani²,

Pradhan³

et al. 2015

Journal of Oral and Maxillofacial Surgery

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Section: Discussionmentioning

confidence: 99%

A Randomized Clinical Trial of the Effects of Submucosal Dexamethasone After Surgery for Mandibular Fractures

Dongol¹,

Jaisani²,

Pradhan³

et al. 2015

Journal of Oral and Maxillofacial Surgery

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“…In contrast, a longer use of steroids is associated with multiple problems, such as skin changes, increased serum glucose, adrenal suppression, disturbed wound healing, and impaired immunity [1]. Various non-medical methods also have been used for edema control, each with limitations.…”

Section: Discussionmentioning

confidence: 99%

“…Any osteotomy, which involves the reflection of a full thickness mucoperiosteal flap, leads to varying degrees of postoperative swelling. An extensive swelling can compromise the surgical outcome as well as patient recovery and the airway [1].…”

Section: Introductionmentioning

confidence: 99%

A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Comparing the Efficacy of Anti-edema Drugs for Edema Control in Orthognathic Surgery Using Digitizer 3-D to Measure Facial Swelling

Tozzi¹,

Santillo

Tartaro

et al. 2014

J. Maxillofac. Oral Surg.

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Introduction Orthognathic surgery involves making several osteotomies. Any osteotomies leads to varying degrees of post-operative swelling. The aim of this study was to evaluate the effectiveness of anti-edema drugs for the control of edema, using Digitizer 3D TM for measuring softtissue thickness, in patients who underwent bimaxillaryorthognathic surgery. Materials and Methods In this double-blinded, randomized, control trial, 24 patients (study group: 12 patients, control group: 12 patients) in whom bimaxillary orthognathic surgery was indicated, were included in this study. All swelling measurements were expressed as total 3-D area of the landmarks (cm 2 ) in T0 pre-operative, T1 first day after surgery, T2 fourth day after surgery, T3 4 months after surgery. For each patient we compared, by adding left and right area, the increase of swelling between T1-T0, T2-T0 and T1-T3. Results The differences T0-T1 are highly significant (p \ 0.01) between group 1 or study group (treated with Venoplant Ò ) and group 2 (control group); the differences T0-T2 are significant (p \ 0.05) between group 1 (treated with Venoplant Ò ) and group 2 (control group). The differences T1-T3 are significant (p \ 0.05) between group 1 (treated with Venoplant Ò ) and group 2 (control group). Discussion The present study suggests that Venoplant Ò significantly decreases postoperative edema in orthognathic surgery, thus precluding long-term corticosteroid use.

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“…Also, hypotensive anesthesia or injection of tranexamic acid can decrease hemorrhage11,12,13. Use of steroid decreases inflammation and swelling14,15. The above variables may influence the amount of postoperative drainage from a closed suction drainage system.…”

Section: Discussionmentioning

confidence: 99%

Comparative analysis of the amount of postoperative drainage after intraoral vertical ramus osteotomy and sagittal split ramus osteotomy

Kim

Chung

Jung

et al. 2014

J Korean Assoc Oral Maxillofac Surg

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ObjectivesThe purpose of this retrospective study was to compare the amount of postoperative drainage via closed suction drainage system after intraoral vertical ramus osteotomy (IVRO) and sagittal split ramus osteotomy (SSRO).Materials and MethodsWe planned a retrospective cohort study of 40 patients selected from a larger group who underwent orthognathic surgery from 2007 to 2013. Mean age (range) was 23.95 (16 to 35) years. Patients who underwent bilateral IVRO or SSRO were categorized into group I or group II, respectively, and each group consisted of 20 patients. Closed suction drainage system was inserted in mandibular osteotomy sites to decrease swelling and dead space, and records of drainage amount were collected. The data were compared and analyzed with independent t-test.ResultsThe closed suction drainage system was removed at 32 hours postoperatively, and the amount of drainage was recorded every 8 hours. In group I, the mean amount of drainage was 79.42 mL in total, with 31.20 mL, 19.90 mL, 13.90 mL, 9.47 mL, and 4.95 mL measured at 0, 8, 16, 24, and 32 hours postoperatively, respectively. In group II, the mean total amount of drainage was 90.11 mL, with 30.25 mL, 25.75 mL, 19.70 mL, 8.50 mL, and 5.91 mL measured at 0, 8, 16, 24, and 32 hours postoperatively, respectively. Total amount of drainage from group I was less than group II, but there was no statistically significant difference between the two groups (P=0.338). There was a significant difference in drainage between group I and group II only at 16 hours postoperatively (P=0.029).ConclusionIVRO and SSRO have different osteotomy design and different extent of medullary exposure; however, our results reveal that there is no remarkable difference in postoperative drainage of blood and exudate.

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Review of evidence for the use of steroids in orthognathic surgery

Cited by 44 publications

References 24 publications

A Randomized Clinical Trial of the Effects of Submucosal Dexamethasone After Surgery for Mandibular Fractures

A Randomized Clinical Trial of the Effects of Submucosal Dexamethasone After Surgery for Mandibular Fractures

A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial Comparing the Efficacy of Anti-edema Drugs for Edema Control in Orthognathic Surgery Using Digitizer 3-D to Measure Facial Swelling

Comparative analysis of the amount of postoperative drainage after intraoral vertical ramus osteotomy and sagittal split ramus osteotomy

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