Review of endogenous endophthalmitis during pregnancy including case series

Sahu, Chinmaya; Kumar, Kshitiz; Sinha, Mumun; Venkata, Amarnath; Majji, Ajit B; Jalali, Subhadra

doi:10.1007/s10792-012-9697-z

Cited by 20 publications

(17 citation statements)

References 19 publications

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“…Similar results have been reported with molds as a common cause of EE in patients on immunosuppressive therapy for hematopoietic stem cell transplantation (HSCT) or for any hematological malignancy [ 30 ]. Patients with lung involvement by Aspergillus are at a specially increased risk for developing EE [ 4 , 30 , 31 ].…”

Section: Reviewmentioning

confidence: 99%

Endogenous endophthalmitis: diagnosis, management, and prognosis

Sadiq

Hassan

Agarwal

et al. 2015

J Ophthal Inflamm Infect

137

146

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Endogenous endophthalmitis is an ophthalmic emergency that can have severe sight-threatening complications. It is often a diagnostic challenge because it can manifest at any age and is associated with a number of underlying predisposing factors. Microorganisms associated with this condition vary along a broad spectrum. Depending upon the severity of the disease, both medical and surgical interventions may be employed. Due to rarity of the disease, there are no guidelines in literature for optimal management of these patients. In this review, treatment guidelines based on clinical data and microorganism profile have been proposed.

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Section: Reviewmentioning

confidence: 99%

Endogenous endophthalmitis: diagnosis, management, and prognosis

Sadiq

Hassan

Agarwal

et al. 2015

J Ophthal Inflamm Infect

137

146

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“…The other species are generally perceived of little clinical significance and they are commonly considered as contaminants in clinical cultures. However, recent reports indicate that these organisms can be responsible for local or systemic infections in humans [ 4 – 11 ].…”

Section: Introductionmentioning

confidence: 99%

Identification and Pathogenic Potential of Clinical Bacillus and Paenibacillus Isolates

et al. 2016

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The soil-related Bacillus and Paenibacillus species have increasingly been implicated in various human diseases. Nevertheless, their identification still poses problems in the clinical microbiology laboratory and, with the exception of Bacillus anthracis and Bacillus cereus, little is known on their pathogenicity for humans. In this study, we evaluated the use of matrix-assisted laser desorption—ionization time of flight mass spectrometry (MALDI-TOF MS) in the identification of clinical isolates of these genera and conducted genotypic and phenotypic analyses to highlight specific virulence properties. Seventy-five clinical isolates were subjected to biochemical and MALDI-TOF MS identification. 16S rDNA sequencing and supplemental tests were used to solve any discrepancies or failures in the identification results. MALDI-TOF MS significantly outperformed classical biochemical testing for correct species identification and no misidentification was obtained. One third of the collected strains belonged to the B. cereus species, but also Bacillus pumilus and Bacillus subtilis were isolated at high rate. Antimicrobial susceptibility testing showed that all the B. cereus, B. licheniformis, B. simplex, B. mycoides, Paenibacillus glucanolyticus and Paenibacillus lautus isolates are resistant to penicillin. The evaluation of toxin/enzyme secretion, toxin-encoding genes, motility, and biofilm formation revealed that B. cereus displays the highest virulence potential. However, although generally considered nonpathogenic, most of the other species were shown to swim, swarm, produce biofilms, and secrete proteases that can have a role in bacterial virulence. In conclusion, MALDI-TOF MS appears useful for fast and accurate identification of Bacillus and Paenibacillus strains whose virulence properties make them of increasing clinical relevance.

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“…In 1 patient the causative organism was Bacillus mycoides , in another patient Klebsiella pneumoniae , and in 2 patients no organism was identified. The patients were treated with systemic, topical, intravitreal ceftazidime, vancomycin and dexamethasone, oral and topical ofloxacin, PPV and oral itraconazole but in all the 4 patients the visual outcome was very poor (NOPL to CF) [ 36 ].…”

Section: Resultsmentioning

confidence: 99%

Metastatic endophthalmitis - Has the trend of causative organism changed in the modern antibiotic era - A Systematic Review

Wadhwani¹,

Mishra²,

Manika³

et al. 2020

rjo

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Endogenous endophthalmitis, EE, a less common form of endophthalmitis, occurs when the microorganisms spread to the eye through the bloodstream, from a septic focus elsewhere in the body, that breaches into the integrity of the eyeball itself. The etiopathogenesis of endogenous endophthalmitis has changed over the past two decades, the aim of this review being to study the changing trends in causative organism in the era of modern antibiotics.

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Review of endogenous endophthalmitis during pregnancy including case series

Cited by 20 publications

References 19 publications

Endogenous endophthalmitis: diagnosis, management, and prognosis

Endogenous endophthalmitis: diagnosis, management, and prognosis

Identification and Pathogenic Potential of Clinical Bacillus and Paenibacillus Isolates

Metastatic endophthalmitis - Has the trend of causative organism changed in the modern antibiotic era - A Systematic Review

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