Review of antibiotic use in respiratory disorders at a regional hospital in Queensland

McGoldrick, Colleen; Ulahannan, Thomas; Krebs, Katrina Lane

doi:10.1016/j.colegn.2016.10.001

Cited by 1 publication

(1 citation statement)

References 23 publications

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“…TANG et al [11] identified that 45% of patients were overprescribed antibiotic therapy. A number of studies have identified inappropriate prescription of antibiotic therapy in the AECOPD patient cohort [12,33,34]. Furthermore, a 2018 Cochrane review concluded that aside from AECOPD patients who are treated in an intensive care unit, the effects of antibiotic therapy use in this patient group is small [35].…”

Section: Discussionmentioning

confidence: 99%

Management of acute COPD exacerbations in Australia: do we follow the guidelines?

et al. 2020

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ObjectiveWe aimed to assess adherence to the Australian national guideline (COPD-X) against audited practice, and to document the outcomes of patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease (COPD) at discharge and 28 days after.MethodsA prospective clinical audit of COPD hospital admission from five tertiary care hospitals in five states of Australia was conducted. Post-discharge follow-up was conducted via telephone to assess for readmission and health status.ResultsThere were 207 admissions for acute exacerbation (171 patients; mean 70.2 years old; 50.3% males). Readmission rates at 28 days were 25.4%, with one (0.6%) death during admission and eight (6.1%) post-discharge within 28 days. Concordance to the COPD-X guidance was variable; 22.7% performed spirometry, 81.1% had blood gases collected when forced expiratory volume in 1 s was <1 L, 99.5% had chest radiography performed, 95.1% were prescribed systemic corticosteroids and 95% were prescribed antibiotic therapy. There were 89.1% given oxygen therapy and 92.6% when arterial oxygen tension was <80 mmHg; 65.6% were given ventilatory assistance when pH was <7.35. Only 32.4% were referred to pulmonary rehabilitation but 76.8% had general practitioner follow-up arranged.ConclusionWhen compared against clinical practice guidelines, we found important gaps in management of patients admitted with COPD throughout tertiary care centres in Australia. Strategies to improve guideline uptake are needed to optimise care.

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