Review: Metabolomics as a prediction tool for plants performance under environmental stress

Villate, Aitor; Nicolas, Markel San; Gallastegi, Mara; Aulas, Pierre-Antoine; Olivares, Maitane; Usobiaga, Aresatz; Etxebarria, Néstor; Aizpurua‐Olaizola, Oier

doi:10.1016/j.plantsci.2020.110789

Cited by 54 publications

(32 citation statements)

References 119 publications

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“…Metabolomics and proteomics have replaced other traditional molecular marker techniques and are often used as tools to determine the expression of vegetation characteristics ( Villate et al, 2021 ). Abiotic stress factors can directly affect the yield of plants and may cause apparent differences in plant characteristics, such as plant performance, growth, metabolism, and protein expression profiles ( Wu et al, 2012 ; Liu et al, 2015 ; Wang et al, 2019 , 2021 ).…”

Section: Introductionmentioning

confidence: 99%

Growth, Stoichiometry, and Palatability of Suaeda salsa From Different Habitats Are Demonstrated by Differentially Expressed Proteins and Their Enriched Pathways

et al. 2021

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Suaeda salsa (L.) Pall., a medicinal and edible plant, has green and red-violet ecotypes that exhibit different phenotypes, tastes, and growth characteristics. However, few studies have focused on these differences from the aspect of differentially expressed proteins under the conditions of different habitats in the field. In this study, two ecotypes of S. salsa from the intertidal (control) and supratidal (treatment) habitats of the Yellow River Delta were selected. A total of 30 individual leaves were mixed into six samples (three biological replicates for each) and subjected to protein extraction by using tandem mass tag-labeled quantitative proteomic technology. A total of 4771 proteins were quantitated. They included 317 differentially expressed proteins (2.0-fold change, p < 0.05), among which 143 were upregulated and the remaining 174 were downregulated. These differentially expressed proteins mainly participated in biological processes, such as response to stimulus, stress, and biotic stimulus; in molecular functions, such as methyltransferase activity, transferase activity, one-C group transfer, and tetrapyrrole binding; and in cell components, such as non-membrane-bound organelles, intracellular non-membrane-bound organelles, chromosomes, and photosystems. The differentially expressed proteins were mainly enriched in eight pathways, among which the ribosome, phenylpropanoid biosynthesis, and photosynthesis pathways had higher protein numbers than the other pathways. The upregulation of differentially expressed proteins related to the ribosome and photosynthesis increased the relative growth rate and reduced the N:P ratio of S. salsa from the supratidal habitat, thereby improving its palatability. By contrast, most of the differentially expressed proteins involved in phenylpropanoid biosynthesis were downregulated in S. salsa from the intertidal habitat. This result indicated that S. salsa from the intertidal habitat might accumulate flavonoids, lignin, and other secondary metabolites in its leaves that confer a bitter taste. However, these secondary metabolites might increase the medicinal value of S. salsa from the intertidal habitat. This work could provide a theoretical basis and data support for the sustainable and high-value utilization of medicinal and edible plants from coastal wetlands.

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Section: Introductionmentioning

confidence: 99%

Growth, Stoichiometry, and Palatability of Suaeda salsa From Different Habitats Are Demonstrated by Differentially Expressed Proteins and Their Enriched Pathways

et al. 2021

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“…Metabolomics is the study of small molecule profile based on the MS and nuclear magnetic resonance (NMR), including metabolites of small molecule substrates, intermediates, and products, which can be a prediction tool for plants’ performances under stress [ 48 ]. A better understanding of the metabolic response mechanisms under drought stress using metabolic QTL and metabolic GWAS could be beneficial to crop improvements [ 49 ].…”

Section: Methods For Mining Genes Related To Drought Tolerancementioning

confidence: 99%

Exploitation of Drought Tolerance-Related Genes for Crop Improvement

Wang

et al. 2021

IJMS

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Drought has become a major threat to food security, because it affects crop growth and development. Drought tolerance is an important quantitative trait, which is regulated by hundreds of genes in crop plants. In recent decades, scientists have made considerable progress to uncover the genetic and molecular mechanisms of drought tolerance, especially in model plants. This review summarizes the evaluation criteria for drought tolerance, methods for gene mining, characterization of genes related to drought tolerance, and explores the approaches to enhance crop drought tolerance. Collectively, this review illustrates the application prospect of these genes in improving the drought tolerance breeding of crop plants.

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“…But, depending on the sample and method of detection, there are exceptions to this. In NMR-based metabolomics studies of blood plasma, for example, macromolecules such as lipoproteins and albumin are reliably detected (Nicholson & Wilson, 2003) It is usual to refer to 'main' and 'secondary' metabolites in plant-based metabolomics (Villate et al, 2021). A primary metabolite is involved directly in growth, development, and reproduction.…”

Section: Tendency Of Metabolitesmentioning

confidence: 99%

“…The collection of gene products generated in the cell are revealed by messenger RNA (mRNA), gene expression data and proteomic analyses, data that represents one aspect of cell function. In comparison, metabolic profiling can offer an instantaneous snapshot of the cell's physiology (Villate et al, 2021) thus, metabolomics offers a clear functional data of the physiological state (Hollywood et at., 2006). In biological sciences, integrating genomics, transcriptomic, proteomic, and metabolomic knowledge to provide a deeper understanding of cellular biology is one of the challenges of systems biology and functional genomics.…”

Section: Introductionmentioning

confidence: 99%

Narrative Review on Metabolomics and Its Extensive Applications in Plant Biotechnology and Oncology

Srivastava¹,

Choure²,

Parsai³

2020

Journal of Innovation in Applied Research

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Metabolomics is that the study of metabolomes in cells, biofluids, tissues, or organisms to comprehensively determine and quantify each endogenous and exogenous low-molecular-weight (<1kDa) metabolites in an exceedingly high-throughput biological system. Together with alternative omics disciplines, metabolomics has several applications for health, disease, precision and personalized medication, single cell, epidemiologic population studies, metabolic phenotyping, and metabolome-wide interaction studies, preciseness metabolomics, and integrative omics, biotechnology, and applied science. The scientific study of chemical processes involving metabolites, small molecule substrates, intermediates and cell metabolism products is termed as Metabolomics. In particular, metabolomics is the systematic study of the unique chemical fingerprints that specific cellular processes leave behind the study of their metabolite profiles in small molecules. In this review we had covered that how metabolomics is being applied in plant biotechnology and in oncology and how its role had helped the research platform in data interpretation.

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Review: Metabolomics as a prediction tool for plants performance under environmental stress

Cited by 54 publications

References 119 publications

Growth, Stoichiometry, and Palatability of Suaeda salsa From Different Habitats Are Demonstrated by Differentially Expressed Proteins and Their Enriched Pathways

Growth, Stoichiometry, and Palatability of Suaeda salsa From Different Habitats Are Demonstrated by Differentially Expressed Proteins and Their Enriched Pathways

Exploitation of Drought Tolerance-Related Genes for Crop Improvement

Narrative Review on Metabolomics and Its Extensive Applications in Plant Biotechnology and Oncology

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