Review—Lab-in-a-Mouth and Advanced Point-of-Care Sensing Systems: Detecting Bioinformation from the Oral Cavity and Saliva

Moonla, Chochanon; Lee, Don Hui; Rokaya, Dinesh; Rasitanon, Natcha; Kathayat, Goma; Lee, Won Young; Kim, Jayoung; Jeerapan, Itthipon

doi:10.1149/2754-2726/ac7533

Cited by 57 publications

(45 citation statements)

References 196 publications

(273 reference statements)

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“…One of the most interesting developments in the sensing of biomarkers (among creatinine is included) is the so-called labin-a-mouth 106,107 (Fig. 13c and d).…”

Section: Applications Of Creatinine Sensors In Point-of-care Devicesmentioning

confidence: 99%

Electrochemical creatinine detection for advanced point-of-care sensing devices: a review

et al. 2022

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“…One of the most interesting developments in the sensing of biomarkers (among creatinine is included) is the so-called labin-a-mouth 106,107 (Fig. 13c and d).…”

Section: Applications Of Creatinine Sensors In Point-of-care Devicesmentioning

confidence: 99%

Electrochemical creatinine detection for advanced point-of-care sensing devices: a review

et al. 2022

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“…Fungi, protozoans, and bacteria are only a few of the microorganisms that fall under this category. Pathogens that enter the body via food, drink, and the air affects over 15 million fatalities worldwide [ 1 , 2 , 3 ]. Virulence and infectious dosage statistics for the COVID-19 virus, a worldwide pandemic, are only beginning to emerge.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Biosensors for Pathogen Detection: An Updated Review

et al. 2022

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Electrochemical biosensors are a family of biosensors that use an electrochemical transducer to perform their functions. In recent decades, many electrochemical biosensors have been created for pathogen detection. These biosensors for detecting infections have been comprehensively studied in terms of transduction elements, biorecognition components, and electrochemical methods. This review discusses the biorecognition components that may be used to identify pathogens. These include antibodies and aptamers. The integration of transducers and electrode changes in biosensor design is a major discussion topic. Pathogen detection methods can be categorized by sample preparation and secondary binding processes. Diagnostics in medicine, environmental monitoring, and biothreat detection can benefit from electrochemical biosensors to ensure food and water safety. Disposable and reusable biosensors for process monitoring, as well as multiplexed and conformal pathogen detection, are all included in this review. It is now possible to identify a wide range of diseases using biosensors that may be applied to food, bodily fluids, and even objects’ surfaces. The sensitivity of optical techniques may be superior to electrochemical approaches, but optical methods are prohibitively expensive and challenging for most end users to utilize. On the other hand, electrochemical approaches are simpler to use, but their efficacy in identifying infections is still far from satisfactory.

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“…Several types of wearable saliva glucose biosensors have been developed in recent years, including the mouthguard type and the pacifier type [ 11 , 12 ]. Nevertheless, the sensing electrode parts of the many developed saliva biosensors are based on screen-printing or metal deposition on a plastic sheet, which may not satisfy the need for an easily disposable sensor.…”

Section: Introductionmentioning

confidence: 99%

A Mediated Enzymatic Electrochemical Sensor Using Paper-Based Laser-Induced Graphene

et al. 2022

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Laser-induced graphene (LIG) has been applied in many different sensing devices, from mechanical sensors to biochemical sensors. In particular, LIG fabricated on paper (PaperLIG) shows great promise for preparing cheap, flexible, and disposable biosensors. Distinct from the fabrication of LIG on polyimide, a two-step process is used for the fabrication of PaperLIG. In this study, firstly, a highly conductive PaperLIG is fabricated. Further characterization of PaperLIG confirmed that it was suitable for developing biosensors. Subsequently, the PaperLIG was used to construct a biosensor by immobilizing glucose oxidase, aminoferrocene, and Nafion on the surface. The developed glucose biosensor could be operated at a low applied potential (−90 mV) for amperometric measurements. The as-prepared biosensor demonstrated a limit of detection of (50–75 µM) and a linear range from 100 µM to 3 mM. The influence of the concentration of the Nafion casting solution on the performance of the developed biosensor was also investigated. Potential interfering species in saliva did not have a noticeable effect on the detection of glucose. Based on the experimental results, the simple-to-prepare PaperLIG-based saliva glucose biosensor shows great promise for application in future diabetes management.

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Review—Lab-in-a-Mouth and Advanced Point-of-Care Sensing Systems: Detecting Bioinformation from the Oral Cavity and Saliva

Cited by 57 publications

References 196 publications

Electrochemical creatinine detection for advanced point-of-care sensing devices: a review

Electrochemical creatinine detection for advanced point-of-care sensing devices: a review

Electrochemical Biosensors for Pathogen Detection: An Updated Review

A Mediated Enzymatic Electrochemical Sensor Using Paper-Based Laser-Induced Graphene

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