Reversible splenial lesion syndrome (RESLES) is a type of lesion that occurs in the middle splenium of the corpus callosum (SCC), and it is characterized by reversible changes of unknown origin. 1,2 This condition has been associated with both infectious and non-infectious disorders, with reports of cases associated with viruses such as influenza, measles, mumps, rotavirus, adenovirus, Epstein-Barr virus, and herpesvirus 6. 3,4 The most common neurological symptoms of RESLES are encephalitis and encephalopathy while idiopathic intracranial hypertension is a rare complication. [5][6][7] Although severe acute respiratory syndromecoronavirus-2 (SARS-CoV-2) primarily affects the lungs, there have been reports of various neurological complications, such as meningitis, ischemic stroke, encephalitis, and Guillain-Barré syndrome, in patients with coronavirus disease-2019 (COVID-19). 8,9 This article reports on the clinical symptoms of a girl with RESLES who was also found to be positive for SARS-CoV-2.
CASE REPORTA 14-year-old girl with no previous medical history presented with symptoms of dizziness, ataxia, and blurred vision for a duration of three weeks. Upon neurological examination, she exhibited confusion and ataxia, but her cranial nerves were intact, and she