Reversible pulmonary hypertension associated with lungworm infection in a young cat

Dirven, M.; Szatmári, Viktor; Ingh, Ted van den; Nijsse, Rolf

doi:10.1016/j.jvc.2012.04.005

Cited by 34 publications

(59 citation statements)

References 20 publications

(11 reference statements)

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“…This result agrees with a previous report describing pulmonary hypertension associated with lungworm infection in a 10-week-old kitten from The Netherlands 2. The presence of two litter mates who also displayed respiratory signs (of undetermined cause) might suggest a common source of infection.…”

supporting

confidence: 92%

Aelurostrongylosis in a young kitten in the UK

Dobromylskyj¹,

Elsheikha

Gunn‐Moore

2019

Veterinary Record

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supporting

confidence: 92%

Aelurostrongylosis in a young kitten in the UK

Dobromylskyj¹,

Elsheikha

Gunn‐Moore

2019

Veterinary Record

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“…Histopathologic pulmonary changes are eosinophilic and neutrophilic infiltrates in the larger and smaller bronchi as well as in the bronchioles, and extensive multifocal granulomatous inflammation in the peribronchial tissue (Dirven et al, 2012). Furthermore, A. abstrusus infection may cause prolonged vasoconstriction mediated by mast cells and histamine release, triggering increased pulmonary vascular resistance and producing pulmonary hypertension (Dirven et al, 2012).…”

Section: Conflict Of Interest Statementmentioning

confidence: 99%

“…Furthermore, A. abstrusus infection may cause prolonged vasoconstriction mediated by mast cells and histamine release, triggering increased pulmonary vascular resistance and producing pulmonary hypertension (Dirven et al, 2012). Since the bronchial mucosa is infiltrated by inflammatory cells due to the presence of A. abstrusus, by using the BWBP, it is possible to determine the degree of bronco-reactivity caused by the worms in the symptomatic infected cat.…”

Section: Conflict Of Interest Statementmentioning

confidence: 99%

First case reported of bronchoconstriction in feline aelurostrongylosis by using barometric whole-body plethysmography

García-Guasch

Manubens

Laporta

et al. 2018

J Hellenic Vet Med Soc

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Symptomatic cats infected by Aelurostrongylus abstrusus show non-specific and respiratory clinical signs, often misdiagnosed as other diseases more prevalent among feline population, such as allergic respiratory disease or heartworm associated respiratory disease (HARD). Clinical signs are due to the pulmonary inflammatory response caused by the eggs shed by the adult females and the migration of the first-stage larvae up the bronchial tree. Barometric whole-body plethysmography (BWBP) is a non-invasive pulmonary function test that allows a dynamic study of breathing patterns by placing the patient within an unrestrained Plexiglas chamber. This is the first report that determines the degree of bronchoconstriction caused by A. abstrusus infection in a cat by using BWBP, showing an increase of baseline measurements of bronchoconstriction indexes (Enhanced pause and Pause) in response to severe bronchial reactivity, a consequence of the airway inflammation caused by the presence of A. abstrusus.

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“…13 The parasite is transmitted indirectly in a life cycle that incorporates mollusks and snails as intermediate hosts, and rodents, frogs, lizards, snakes, and birds as paratenic hosts. 14,15 Cats are infected when they consume an intermediate or paratenic host containing larvae; these larvae then migrate to the lungs, mature to their adult forms, and produce larvae that migrate to the pharynx and are passed into the feces, thus completing the cycle. 13 The hatching of eggs and migration of larvae are responsible for most clinical signs.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of Aelurostrongylus abstrusus verminous pneumonia via sonography-guided fine-needle pulmonary parenchymal aspiration in a cat

Gambino

Hiebert

Johnson

et al. 2016

Journal of Feline Medicine and Surgery Open Reports

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Case summary A 9-year-old, male neutered, indoor–outdoor domestic shorthair cat from the northern Alabama countryside presented for a 3 week history of coughing, lethargy and an episode of self-resolving dyspnea that occurred 1 week prior to presentation. Three-view thoracic radiographs revealed a moderate-to-severe, diffuse, mixed bronchial to structured interstitial (miliary-to-nodular) pulmonary pattern in all lung lobes with peribronchial cuffing and multifocal areas of mild patchy alveolar opacity. Ultrasound-guided evaluation and fine-needle aspiration of the caudodorsal lung parenchyma was performed with sedation. Cytology revealed many widely scattered Aelurostrongylus abstrusus larvae and ova. Upon the confirmed diagnosis of A abstrusus verminous pneumonia, treatment with fenbendazole and selamectin resulted in complete resolution of clinical signs within 6 weeks of the initial diagnosis.Relevance and novel information We report herein the first documented case in the Americas of A abstrusus verminous pneumonia diagnosed via cytologic evaluation of an in vivo, percutaneous ultrasound-guided fine-needle aspirate of affected lung. Additionally, to our knowledge, we offer the first account of the sonographic (pulmonary) features of the disease.

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Reversible pulmonary hypertension associated with lungworm infection in a young cat

Cited by 34 publications

References 20 publications

Aelurostrongylosis in a young kitten in the UK

Aelurostrongylosis in a young kitten in the UK

First case reported of bronchoconstriction in feline aelurostrongylosis by using barometric whole-body plethysmography

Diagnosis of Aelurostrongylus abstrusus verminous pneumonia via sonography-guided fine-needle pulmonary parenchymal aspiration in a cat

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