Reversible optosensing in packed flow-through detectors: flow injection or chromatography?

Růžička, Jaromír; Christian, Gary D.

doi:10.1016/s0003-2670(00)83535-7

Cited by 22 publications

(2 citation statements)

References 12 publications

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“…The pioneering step in the miniaturization of flow analysis was a design of integrated microconduits with miniature detectors and a large hydraulic part for transport of solutions [70,71]. Other attempts included the replacement of typical peristaltic pumps with small syringes or piezoelectric pumping devices [72] and the incorporation of various parts of typical flow systems (flow-through reactors, detectors [73]) into a rotary valve for sample injection in Lab-on-Valve [74].…”

Section: Microsystems In Flow Analysismentioning

confidence: 99%

Flow Analysis as Advanced Branch of Flow Chemistry

Trojanowicz¹

2013

Mod Chem Appl

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The effectiveness of the carrying out chemical reactions, especially in terms of syntheses conducted in the laboratory or on a technological scale, is a primary target of the optimization of chemical conditions and physicochemical parameters of a given process. Since the publication of pioneering works in the beginning of 1970s, it is an increasingly accepted concept that carrying out chemical reactions in continuously flowing streams rather than in batch configuration has numerous advantages, hence flow chemistry can be at present considered as a separate and rapidly increasing area of modern chemistry. Four decades of the development of those methods resulted in thousands of original research works, numerous reported attractive technologies, and also in the presence of numerous specialized instruments on the market.

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Section: Microsystems In Flow Analysismentioning

confidence: 99%

Flow Analysis as Advanced Branch of Flow Chemistry

Trojanowicz¹

2013

Mod Chem Appl

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“…bead size > 30 mm) have been designed for this application. However, such configurations and packing sorbent may be regarded as far from optimum for several reasons: (1) compaction (or even clogging) of the packing material with time increases flow impedance and causes displacement of the retention zone from the observation field, which results in a reduction of the dynamic range; backflushing elution is generally required to avoid this undesirable effect; (2) small particle diameters are desirable to offer a high specific surface area; nevertheless, the excessive back-pressure and the light attenuation, 24 which worsens the signal-to-noise ratio, make their utilization in flow-through spectrophotometric cells difficult; and (3) after several runs, the flow-cells must be re-filled with a freshly prepared sorbent slurry, which is inconvenient and time consuming.…”

Section: Introductionmentioning

confidence: 99%