Reversible Myelopathy in a 34-Year-Old Man With Vitamin B12 Deficiency

Pittock, Sean J.; Payne, Troy A.; Harper, Christine M.

doi:10.4065/77.3.291

Cited by 39 publications

(28 citation statements)

References 25 publications

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“…Therefore, certain substances need to be present at the injured area for optimal cell proliferation (32,33). The presence of cyanocobalamin (vitamin B 12 ) in Rheumazin is important due to its role as a co-enzyme in DNA synthesis, together with the presence of dexamethasone which has neuron protective activity (7).…”

Section: Discussionmentioning

confidence: 99%

Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery

Barroso¹,

Lima²,

Guzzo³

et al. 2006

Braz J Med Biol Res

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Third molar extraction is a common procedure frequently accompanied by moderate or severe pain, and involves sufficient numbers of patients to make studies relatively easy to perform. The aim of the present study was to determine the efficacy and safety of the therapeutic combination of 10 mg piroxicam, 1 mg dexamethasone, 35 mg orphenadrine citrate, and 2.5 mg cyanocobalamin (Rheumazin ® ) when compared with 20 mg piroxicam alone (Feldene ® ) in mandibular third molar surgery. Eighty patients scheduled for removal of the third molar were included in this randomized and double-blind study. They received (vo) Rheumazin or Feldene 30 min after tooth extraction and once daily for 4 consecutive days. Pain was determined by a visual analogue scale and by the need for escape analgesia (paracetamol). Facial swelling was evaluated with a measuring tape and adverse effects and patient satisfaction were recorded. There was no statistically significant difference in facial swelling between Rheumazin and Feldene (control group). Both drugs were equally effective in the control of pain, with Rheumazin displaying less adverse effects than Feldene. Therefore, Rheumazin appears to provide a better risk/ benefit ratio in the mandibular molar surgery. Since the side effects resulting from nonsteroidal anti-inflammatory drug administration are a severe limitation to the routine use of these drugs in clinical practice, our results suggest that Rheumazin can be a good choice for third molar removal treatment.

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Section: Discussionmentioning

confidence: 99%

Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery

Barroso¹,

Lima²,

Guzzo³

et al. 2006

Braz J Med Biol Res

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“…The more commonly reported MR findings of SCD are increased T2-weighted signal in the posterior and lateral columns of the cervical and thoracic spinal cord [5,6]. Involvement of the anterior columns as seen in our patient has been described previously in a few cases [7,8] and may indicate a more advanced disease.…”

Section: Discussionmentioning

confidence: 61%

Rare sensory and autonomic disturbances associated with vitamin B12 deficiency

Puntambekar

Basha

Zak

et al. 2009

Journal of the Neurological Sciences

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“…1 Magnetic resonance imaging findings have often demonstrated an increased T2-weighted signal in the posterior and lateral columns of the cervical and thoracic spine and, rarely, in the anterior column. 2,3 The neurological presentation is most commonly that of sub-acute combined degeneration of the spinal cord, leading to myelopathy. 3 Depression, psychosis and dementia have also been associated with vitamin B 12 deficiency.…”

Section: Discussionmentioning

confidence: 99%

Vitamin B₁₂ deficiency: an unusual cause of vocal fold palsy

2011

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To our knowledge, this is the first reported case of unilateral vocal fold palsy secondary to vitamin B12 deficiency. Central and peripheral neuropathies have been described; however, other than the optic nerve, the cranial nerves are very rarely affected. It is important to consider vitamin B12 deficiency as a cause, as speedy identification and treatment can help prevent permanent neurological damage.

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Reversible Myelopathy in a 34-Year-Old Man With Vitamin B12 Deficiency

Cited by 39 publications

References 25 publications

Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery

Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery

Rare sensory and autonomic disturbances associated with vitamin B12 deficiency

Vitamin B₁₂ deficiency: an unusual cause of vocal fold palsy

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Reversible Myelopathy in a 34-Year-Old Man With Vitamin B12 Deficiency

Cited by 39 publications

References 25 publications

Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery

Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery

Rare sensory and autonomic disturbances associated with vitamin B12 deficiency

Vitamin B12 deficiency: an unusual cause of vocal fold palsy

Contact Info

Product

Resources

About

Vitamin B₁₂ deficiency: an unusual cause of vocal fold palsy