Reversible detection of hypochlorite using the deprotonation–protonation strategy: a search for new building blocks

Abstract

<p>A variety of building blocks having ‘acidic protons’ and potential to undergo self-assembly have been synthesized for reversible detection of hypochlorite in aqueous media using deprotonation-protonation as the detection strategy....</p>

ESIPT‐based AIE luminogens: Design strategies, applications, and mechanisms

“…Akin to Schiff base, azine can also act as an AIE unit and proton acceptor to form intramolecular hydrogen bonding with the o ‐hydroxyl group on benzene (Scheme 2D,E), [ 40, 41, 48, 54, 61, 67, 75, 79, 82, 84, 85, 87, 91, 92, 94, 95, 97, 98, 104– 106, 111, 115, 117, 173–178 ] naphthalene (Scheme 2F), [ 49, 80, 174 ] and coumarin rings (Scheme 2H). [ 93, 179 ] Among these compounds, symmetric salicylaldehyde azine derivatives (SAA, Scheme 2E) [ 41, 61, 75, 79, 87, 91, 92, 94, 95, 97, 98, 104–106, 111, 115 , 117, 175–178 ] have gained the most popularity in construction of ESIPT‐based AIEgens because they are easily synthesized from salicylaldehyde derivatives and hydrazine hydrate even in one step.…”

“…A significant advantage of symmetric SAA is that the hydroxyl group can be easily modified by various protecting and targeting groups, making it suitable in the detection of small and biological molecules. [ 61, 75, 79, 91, 92, 84, 95, 97, 98, 104–106, 111, 115, 117, 175–178 ] Moreover, a series of asymmetric SAA derivatives, [ 40, 54, 67, 84, 85, 173, 174 ] including keto‐salicylaldehyde azine (KSA), [ 48, 82 ] have also been developed as ESIPT‐based AIEgens and applied in different fields. The emergence of KSA makes the synthesization of asymmetric SAA become easier, thus opening the avenues for further development of asymmetric SAA as ESIPT‐based AIEgens.…”

“…The development of ESIPT‐based AIEgens has attracted great attention in the fields of physics, chemistry, and biology science. A growing number of ESIPT‐based AIEgens have been developed and applied in the detection of cations, [ 28–57 ] anions, [ 34, 35, 41, 43, 58–68 ] and small molecules, [ 69–76 ] bioimaging in the living cell and in vivo, [ 77–116 ] drug delivery systems (DDS), [ 44, 117–119 ] liquid crystal, [ 120–122 ] white light emitters, [ 123–127 ] and latent fingerprinting. [ 56, 128–131 ]…”

“…The development of ESIPT-based AIEgens has attracted great attention in the fields of physics, chemistry, and biology science. A growing number of ESIPT-based AIEgens have been developed and applied in the detection of cations, anions, [34,35,41,43,[58][59][60][61][62][63][64][65][66][67][68] and small molecules, [69][70][71][72][73][74][75][76] bioimaging in the living cell and in vivo, drug delivery systems (DDS), [44,[117][118][119] liquid crystal, [120][121][122] white light emitters, [123][124][125][126][127] and latent fingerprinting. [56,[128][129][130][131] Fluorescence quenching of AIEgens in dilute solutions resulted from the consumption of excited-state energies by intramolecular motions, including vibrational motions, rotational motions, and both of them.…”

Ruthenium(II) Complex‐based Highly Specific Luminescence Light‐up Probe for Detecting HOCl via C(sp2)‐H Chlorination

“…While there have been several reports on catalytic C−H functionalization of 1,2,3‐triazoles at the 5‐position, [45] there is no report on luminescent ROS detection via C−H chlorination to date. Although most of the reported probes for HOCl are based on organic molecules, [46–53] metal complex‐based probes are still rare [54–63] …”