Reversible Corticobasal Syndrome due to Coeliac Disease

Paramanandam, Vijayashankar; Hadjivassiliou, Marios; Olszewska, Diana A.; Munteanu, Tudor; Williams, Laura; Magennis, Brian; Fearon, Conor; O’Connell, Martin; Sarrigiannis, Ptolemaios G.; Lynch, Tim

doi:10.1002/mdc3.12659

Cited by 2 publications

(1 citation statement)

References 10 publications

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“…Rarely, chorea can be associated with gluten sensitivity and coeliac disease 3. Gluten-related movement disorders may improve or resolve after dietary gluten removal, whereas its persistence in some patients may reflect permanent neuronal damage (eg, loss of Purkinje cells in gluten ataxia) 3–5…”

Section: Discussionmentioning

confidence: 99%

Coeliac disease presenting with chorea

et al. 2019

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Chorea can be genetic or acquired, and often leads to a challenging diagnostic conundrum. In a significant proportion, there is no specific identifiable cause. Chorea is a rare but potentially reversible neurological manifestation of coeliac disease, usually presenting insidiously and often presumed to be associated with typical gastrointestinal symptoms. We report a patient with rapidly progressive generalised chorea, but without preceding gastrointestinal symptoms, who was subsequently diagnosed with coeliac disease. A gluten-free diet resulted in complete resolution of the chorea.

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Section: Discussionmentioning

confidence: 99%

Coeliac disease presenting with chorea

et al. 2019

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Myoclonus Associated with Celiac Disease Responsive to Anti-Epileptics and a Gluten-Free Diet

Hanna

Tandon

Gallinger

2021

Case Rep Gastroenterol

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We report on the case of a 61-year-old male who initially presented with a progressive myoclonus and an intention tremor and was subsequently diagnosed with celiac disease. His neurological symptoms improved with anti-epileptic therapy and a gluten-free diet. Possible explanations include a milder disease phenotype or an epileptic component to his myoclonic movement disorder. This case highlights findings of a progressive myoclonic movement disorder, likely linked to celiac disease, and stresses the importance of a gluten-free diet in the management of the neurological manifestations of celiac disease.

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Reversible Corticobasal Syndrome due to Coeliac Disease

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Cited by 2 publications

References 10 publications

Coeliac disease presenting with chorea

Coeliac disease presenting with chorea

Myoclonus Associated with Celiac Disease Responsive to Anti-Epileptics and a Gluten-Free Diet

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