Reversible Cardiomyopathy Associated with Cocaine Intoxication

Chokshi, Saurabh K.; Moore, Richard A.; Pandian, Natesa G.; Isner, Jeffrey M.

doi:10.7326/0003-4819-111-12-1039

Cited by 142 publications

(35 citation statements)

References 8 publications

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“…Other reported cardiac complications are myocarditis 874 and cardiomyopathy. 876,877 6.6.2. Treatment When a patient with or suspected of cocaine use is seen in the ED with chest pain compatible with myocardial ischemia and ST-segment elevation, sublingual NTG or a calcium channel blockers (e.g., diltiazem 20 mg IV) should be administered.…”

Section: Coronary Artery Spasm With Cocaine Usementioning

confidence: 99%

2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

Anderson¹,

Adams²,

Antman³

et al. 2011

Circulation

681

367

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Section: Coronary Artery Spasm With Cocaine Usementioning

confidence: 99%

2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

Anderson¹,

Adams²,

Antman³

et al. 2011

Circulation

681

367

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“…This is often referred to as transient toxic cardiomyopathy associated with cocaine use, similar to catecholamine cardiomyopathy of pheochromocytoma and possible left apical ballooning syndrome. 24,25 Possible explanations include excess catecholamines leading to myocyte damage due to calcium overload or by transient coronary vasoconstriction with ischemia and subsequent myocyte death. There is still a debate as to whether the appearance of a mononuclear cell infiltrate is a secondary reaction to myocyte death or whether it represents a primary hypersensitivity reaction to cocaine, with a resultant myocarditis.…”

Section: Cardiomyopathy and Myocarditismentioning

confidence: 99%

Cocaine and the Heart

Maraj

Figueredo

Morris

2010

Clinical Cardiology

115

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The use of cocaine may be associated with either acute or chronic toxicity, and approximately 5% to 10% of emergency department visits in the United States are believed to be secondary to cocaine usage. Chest pain is the most common cocaine‐related medical problem, leading to the evaluation of approximately 64 000 patients annually for possible myocardial infarction, of which approximately 57% are admitted to the hospital, resulting in an annual cost greater than $83 million. There is a plethora of cocaine‐related cardiovascular complications, including acute myocardial ischemia and infarction, arrhythmias, sudden death, myocarditis, cardiomyopathy, hypertension, aortic ruptures, and endocarditis. There is no evidence to suggest that preexisting vascular disease is a prerequisite for the development of a cocaine‐related cardiovascular event, although it may be a potentiating factor, as may be nicotine and alcohol. Copyright © 2010 Wiley Periodicals, Inc.

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“…If the clinical suspicion is high, the diagnosis of cocaine use should be investigated with a urine screen for cocaine and its metabolites. The typical patient with cocaine cardiomyopathy is a young male smoker who presents with signs of adrenergic excess (5,10). With acute binge use of cocaine, the patient may present with acute congestive heart failure and pulmonary edema.…”

Section: Figure 2 X-ray Findings Of Enlarged Heart Silhouettementioning

confidence: 99%

Cocaine cardiomyopathy: A case report

Greco¹,

Zhivadinovik²

2014

SANAMED

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Abstract:Cocaine is the second most common illicit drug used and the most frequent cause of drug related deaths. The use of cocaine is associated with both, acute and chronic complications, that may involve any system, but the most common system affected is cardiovascular one. Cocaine cardiomyopathy may result from the use of cocaine.This article presents a first case in Republic of Macedonia of 24-year-old male with reversible cocaine-related cardiomyopathy. Clinical presentation, laboratory, X-ray, ultrasound findings and treatment are reviewed.

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Reversible Cardiomyopathy Associated with Cocaine Intoxication

Cited by 142 publications

References 8 publications

2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

2011 ACCF/AHA Focused Update Incorporated Into the ACC/AHA 2007 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction

Cocaine and the Heart

Cocaine cardiomyopathy: A case report

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