Abstract:Objective Chronic Interstitial Nephritis in Agricultural Communities (CINAC) causes major morbidity and mortality for farmers in North-Central province (NCP) of Sri Lanka. To prevent the CINAC, reverse osmosis (RO) plants are established to purify the water and reduce the exposure to possible nephrotoxins through drinking water. We assessed RO plant maintenance and efficacy in NCP. Methods We have interviewed 10 RO plant operators on plant establishment, maintenance, usage and funding. We also measured total d… Show more
“…However, the technology requires application after critically characterizing the source water, otherwise the technology may become unusable. Presently, community scale membrane treatment plants that are based on reverse osmosis (RO) are installed throughout the CKDu prevailing areas [16]. This study developed a WQI values for rapid demarcation of the source to suggest an appropriate treatment methods.…”
Section: Resultsmentioning
confidence: 99%
“…Presently, over 500 small scale (0.5 m 3 /day–3 m 3 /day of treated water) RO drinking water treatment stations are in operation in the CKDu prevailing areas, which sell water at the nominal price (US $ 0.01/L) or provided for free (with the support from individual donors or organizations). As most of the plants are operated by different individuals and/or community organizations, no two plant necessarily follow the same protocols in plant operation, maintenance, and management [16]. During rainy seasons, people tend to use rain water for consumption, which results in a considerable reduction in water demand/production occurring in most of these RO plants during the wet season.…”
This study investigated the water quality of the groundwater that was collected from the chronic kidney disease of unknown etiology (CKDu) prevailing areas in the dry zone of Sri Lanka to assess its suitability for drinking purposes, and for the first time a Water Quality Index (WQI) with emphasis on proposing appropriate drinking water treatment method was developed. A total of 88 groundwater samples were collected in dry (December 2016) and wet (May 2017) seasons; high concentrations of water hardness, fluoride, salinity, dissolved organic carbon (DOC), and the general alkaline nature of water were the main issues that were observed for disease incidence. The chemical weathering of the underlying bedrock, followed by ion exchange and precipitation processes, primarily controlled groundwater geochemistry. During the 1985–2017 period, the variations of the annual rainfall and temperature were minimal, which suggests no evidence for major climatic changes within the study areas. Almost all of the samples from the CKDu regions show a low alkali hazard and most of the samples show a medium to high salinity hazard. The DOC of the studied samples was mainly composed of the organic fractions in the following order, as fulvic acids > humic acids > aromatic protein II > soluble microbial by-products, and the molecular weights (MW) of these fractions ranged from 100–3000 Da. Based on the water quality index (WQI) calculations, it was found that only 3.8% in the wet season and 2.6% in the dry season of total water samples were categorized as the “excellent” type, and all other water sources require a further treatment before consumption. As there is an urgent need for establishing proper long-term drinking water treatment technology for the CKDu affected area, these findings can be used as benchmark of raw water quality in the design processes of treatment plants.
“…However, the technology requires application after critically characterizing the source water, otherwise the technology may become unusable. Presently, community scale membrane treatment plants that are based on reverse osmosis (RO) are installed throughout the CKDu prevailing areas [16]. This study developed a WQI values for rapid demarcation of the source to suggest an appropriate treatment methods.…”
Section: Resultsmentioning
confidence: 99%
“…Presently, over 500 small scale (0.5 m 3 /day–3 m 3 /day of treated water) RO drinking water treatment stations are in operation in the CKDu prevailing areas, which sell water at the nominal price (US $ 0.01/L) or provided for free (with the support from individual donors or organizations). As most of the plants are operated by different individuals and/or community organizations, no two plant necessarily follow the same protocols in plant operation, maintenance, and management [16]. During rainy seasons, people tend to use rain water for consumption, which results in a considerable reduction in water demand/production occurring in most of these RO plants during the wet season.…”
This study investigated the water quality of the groundwater that was collected from the chronic kidney disease of unknown etiology (CKDu) prevailing areas in the dry zone of Sri Lanka to assess its suitability for drinking purposes, and for the first time a Water Quality Index (WQI) with emphasis on proposing appropriate drinking water treatment method was developed. A total of 88 groundwater samples were collected in dry (December 2016) and wet (May 2017) seasons; high concentrations of water hardness, fluoride, salinity, dissolved organic carbon (DOC), and the general alkaline nature of water were the main issues that were observed for disease incidence. The chemical weathering of the underlying bedrock, followed by ion exchange and precipitation processes, primarily controlled groundwater geochemistry. During the 1985–2017 period, the variations of the annual rainfall and temperature were minimal, which suggests no evidence for major climatic changes within the study areas. Almost all of the samples from the CKDu regions show a low alkali hazard and most of the samples show a medium to high salinity hazard. The DOC of the studied samples was mainly composed of the organic fractions in the following order, as fulvic acids > humic acids > aromatic protein II > soluble microbial by-products, and the molecular weights (MW) of these fractions ranged from 100–3000 Da. Based on the water quality index (WQI) calculations, it was found that only 3.8% in the wet season and 2.6% in the dry season of total water samples were categorized as the “excellent” type, and all other water sources require a further treatment before consumption. As there is an urgent need for establishing proper long-term drinking water treatment technology for the CKDu affected area, these findings can be used as benchmark of raw water quality in the design processes of treatment plants.
“…This would, for example, help reduce water pollution and prevent the overgrowth of toxin-producing cyanobacteria [156]. Switching from chemical-based phosphate fertilizers to organic fertilizers would also help reduce arsenic exposure [167].…”
Section: Discussionmentioning
confidence: 99%
“…Government agencies and other institutions can conduct environmental and bio-monitoring in CKDu-affected areas to better understand local factors in the web of causation. Efforts to treat contaminated water with reverse osmosis filters could be expanded [167]. With regard to the treatment of CKDu, it is beyond the scope of this paper to discuss specific drugs and protocols.…”
Chronic kidney disease of unknown etiology (CKDu) is a global epidemic. Sri Lanka has experienced a doubling of the disease every 4 or 5 years since it was first identified in the North Central province in the mid-1990s. The disease primarily affects people in agricultural regions who are missing the commonly known risk factors for CKD. Sri Lanka is not alone: health workers have reported prevalence of CKDu in Mexico, Nicaragua, El Salvador, and the state of Andhra Pradesh in India. A global search for the cause of CKDu has not identified a single factor, but rather many factors that may contribute to the etiology of the disease. Some of these factors include heat stroke leading to dehydration, toxic metals such as cadmium and arsenic, fluoride, low selenium, toxigenic cyanobacteria, nutritionally deficient diet and mycotoxins from mold exposure. Furthermore, exposure to agrichemicals, particularly glyphosate and paraquat, are likely compounding factors, and may be the primary factors. Here, we argue that glyphosate in particular is working synergistically with most of the other factors to increase toxic effects. We propose, further, that glyphosate causes insidious harm through its action as an amino acid analogue of glycine, and that this interferes with natural protective mechanisms against other exposures. Glyphosate’s synergistic health effects in combination with exposure to other pollutants, in particular paraquat, and physical labor in the ubiquitous high temperatures of lowland tropical regions, could result in renal damage consistent with CKDu in Sri Lanka.
“…Relatively little has been written specifically about the implementation and acceptance of preventive efforts to replace drinking water sources in Sri Lanka. Jayasumana et al (2016) examine aspects of the operation of reverse osmosis treatment for CKDu prevention, but focus on a sample of only 10 treatment plants in two CKDu-affected districts. Rajakarunanayake and Ariyananda (2018) survey the challenges of sustaining rainwater harvesting systems used by about 950 households with a focus on three districts, only two of which are considered to be CKDu affected.…”
Balasubramanya (2021) Community response to the provision of alternative water supplies: A focus on chronic kidney disease of unknown aetiology (CKDu) in rural
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