Reverse engineering DNA origami nanostructure designs from raw scaffold and staple sequence lists

Shirt-Ediss, Ben; Connolly, Jordan; Elezgaray, Juan; Torelli, Emanuela; Navarro, Silvia Adriana; Bacardit, Jaume; Krasnogor, Natalio

doi:10.1016/j.csbj.2023.07.011

Cited by 2 publications

(2 citation statements)

References 46 publications

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“…Over the last two decades, hundreds of thousands of staples have likely been synthesized and acquired around the world in quantities that often outlast the length of a project (or a PhD thesis). Reverse engineering a DNA nanostructure from a given set of staples is now possible; perhaps these existing staples can be repurposed and remixed to create new viable architectures. Recycling the same scaffold into forming a new shape was recently shown by Pfeifer et al Such dynamism has the capability to make DNA nanotechnology an even “greener” technology while also be leveraged for multiplexed sensing and cellular applications.…”

Section: Conclusion and Future Outlookmentioning

confidence: 99%

Dominant Analytical Techniques in DNA Nanotechnology for Various Applications

Neyra,

Everson,

Mathur

2024

Anal. Chem.

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DNA nanotechnology is rapidly gaining traction in numerous applications, each bearing varying degrees of tolerance to the quality and quantity necessary for viable nanostructure function. Despite the distinct objectives of each application, they are united in their reliance on essential analytical techniques, such as purification and characterization. This tutorial aims to guide the reader through the current state of DNA nanotechnology analytical chemistry, outlining important factors to consider when designing, assembling, purifying, and characterizing a DNA nanostructure for downstream applications.

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Section: Conclusion and Future Outlookmentioning

confidence: 99%

Dominant Analytical Techniques in DNA Nanotechnology for Various Applications

Neyra,

Everson,

Mathur

2024

Anal. Chem.

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“…This method can also be used in designing pedagogical processes for education in robotics in schools [35]. Regarding deeper research, this method can be applied to designing DNA origami at the nanostructure level [36]. The reverse engineering method can be integrated with multi-criteria decision-making methods in the classic car remanufacturing process [37].…”

Section: Introductionmentioning

confidence: 99%

Design and manufacturing optimization of herbal drink crystallization machine using reverse engineering method

Santoso,

Islahudin,

Wijaya

2023

Jurnal Optimasi Sistem Industri

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This article explains the design and manufacture of a herbal drink powder crystallization machine at Menik Jaya MSMEs. The problem with this research stems from the large number of defective products produced in the form of herbal powder that is burnt and lumpy. This is because production staff still manually stir the process continuously without stopping, causing fatigue due to work and impacting the quality of the process. So that the optimal design and manufacture of the crystallization machine is obtained where the dimensions of the machine are 130 cm high, 100 cm long and wide, machine legs height is 62 cm, stove height is 87 cm from the base and the stove pan handle width is 12 cm. Regarding engine performance, the ideal electric capacity of the motor is 60 watts with a stirrer and pan made from a combination of wood and AISI 3195 stainless steel. The pully uses 2 types of sizes, if the volume of raw material is small then a 4 cm pully is used with 10 Rpm rotation speed and 0,052 Nm torque value, while for large volumes a 6 cm pully is used with 15 Rpm rotation speed and 0,038 Nm torque value.

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Reverse engineering DNA origami nanostructure designs from raw scaffold and staple sequence lists

Cited by 2 publications

References 46 publications

Dominant Analytical Techniques in DNA Nanotechnology for Various Applications

Dominant Analytical Techniques in DNA Nanotechnology for Various Applications

Design and manufacturing optimization of herbal drink crystallization machine using reverse engineering method

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