Reversal of rocuronium-induced neuromuscular block: is it time for sugammadex to replace neostigmine?

Carron, Michele; Cassai, Alessandro De; Ieppariello, Giovanna

doi:10.1016/j.bja.2019.04.045

Cited by 3 publications

(2 citation statements)

References 20 publications

(33 reference statements)

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“…Readmission data were not reported in the Mouri and colleagues' study (26). Whether sugammadex results in further potential economic benefit in patients with myasthenia gravis will depend on readmission costs and the extent of reduction in 30-day unplanned readmission rates in these patients (34).…”

mentioning

confidence: 95%

Sugammadex in the management of myasthenic patients undergoing surgery: beyond expectations

Carron¹,

Cassai²,

Linassi³

2019

Ann Transl Med

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mentioning

confidence: 95%

Sugammadex in the management of myasthenic patients undergoing surgery: beyond expectations

Carron¹,

Cassai²,

Linassi³

2019

Ann Transl Med

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“…Many surgical, anesthetic, and preoperative factors are involved in their onset; the use of neuromuscular blocking (NMB) agents and the occurrence of residual neuromuscular block (RNMB) is a proven cause in the majority of recent studies 3 – 5 . However, the use of pharmacological reversal of NMB, and particularly the comparison between neostigmine and sugammadex, remains a controversial factor 6 – 8 .…”

Section: Introductionmentioning

confidence: 99%

Model for predicting early and late-onset postoperative pulmonary complications in perioperative patients receiving neuromuscular blockade: a secondary analysis

Oliver-Forniés¹,

Ramírez-Rodríguez²,

Aragón-Benedí³

et al. 2023

Sci Rep

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Pulmonary complications continue to be the most common adverse event after surgery. The main objective was to carry out two independent predictive models, both for early pulmonary complications in the Post-Anesthesia Care Unit and late-onset pulmonary complications after 30 postoperative days. The secondary objective was to determine whether presenting early complications subsequently causes patients to have other late-onset events. This is a secondary analysis of a cohort study. 714 patients were divided into four groups depending on the neuromuscular blocking agent, and spontaneous or pharmacological reversal. Incidence of late-onset complications if we have not previously had any early complications was 4.96%. If the patient has previously had early complications the incidence of late-onset complications was 22.02%. If airway obstruction occurs, the risk of atelectasis increased from 6.88 to 22.58% (p = 0.002). If hypoxemia occurs, the incidence increased from 5.82 to 21.79% (p < 0.001). Based on our predictive models, we conclude that diabetes mellitus and preoperative anemia are two risk factors for early and late-onset postoperative pulmonary complications, respectively. Hypoxemia and airway obstruction in Post-Anesthesia Care Unit increased four times the risk of the development of pneumonia and atelectasis at 30 postoperative days.

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Letter Regarding: Comparison of the Effects of Neostigmine and Sugammadex on Colonic Anastomotic Strength in Rats

Buonanno

Vargas

Marra

et al. 2020

Journal of Surgical Research

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Reversal of rocuronium-induced neuromuscular block: is it time for sugammadex to replace neostigmine?

Cited by 3 publications

References 20 publications

Sugammadex in the management of myasthenic patients undergoing surgery: beyond expectations

Sugammadex in the management of myasthenic patients undergoing surgery: beyond expectations

Model for predicting early and late-onset postoperative pulmonary complications in perioperative patients receiving neuromuscular blockade: a secondary analysis

Letter Regarding: Comparison of the Effects of Neostigmine and Sugammadex on Colonic Anastomotic Strength in Rats

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