Reversal of multidrug resistance by amphiphilic morning glory resin glycosides in bacterial pathogens and human cancer cells

Lira-Ricárdez, Jesús; Pereda‐Miranda, Rogelio

doi:10.1007/s11101-019-09631-1

Cited by 17 publications

(15 citation statements)

References 95 publications

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“…Resin glycosides show the ideal structural features associated with multidrug-resistant efflux-pump substrates [ 101 ]. Pescapreins II and III ( 58 and 59 ), stoloniferin III ( 61 ), pescapreins XVIII–XX ( 76 – 78 ), stoloniferins IX and X ( 79 and 80 ), and murucoidin VI ( 81 ), which were isolated from the chloroform extract of I. pes-caprae whole plant have been tested in vitro for their antibacterial and resistance-modulating activity against S. aureus strains possessing multidrug-resistance (MDR) efflux mechanisms [ 39 ].…”

Section: Bioactivities Of I Pes-capraementioning

confidence: 99%

A Medicinal Halophyte Ipomoea pes-caprae (Linn.) R. Br.: A Review of Its Botany, Traditional Uses, Phytochemistry, and Bioactivity

et al. 2022

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Ipomoea pes-caprae (Linn.) R. Br. (Convolvulaceae) is a halophytic plant that favorably grows in tropical and subtropical countries in Asia, America, Africa, and Australia. Even though this plant is considered a pan-tropical plant, I. pes-caprae has been found to occur in inland habitats and coasts of wider areas, such as Spain, Anguilla, South Africa, and Marshall Island, either through a purposeful introduction, accidentally by dispersal, or by spreading due to climate change. The plant parts are used in traditional medicine for treating a wide range of diseases, such as inflammation, gastrointestinal disorders, pain, and hypertension. Previous phytochemical analyses of the plant have revealed pharmacologically active components, such as alkaloids, glycosides, steroids, terpenoids, and flavonoids. These phytoconstituents are responsible for the wide range of biological activities possessed by I. pes-caprae plant parts and extracts. This review arranges the previous reports on the botany, distribution, traditional uses, chemical constituents, and biological activities of I. pes-caprae to facilitate further studies that would lead to the discovery of novel bioactive natural products from this halophyte.

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Section: Bioactivities Of I Pes-capraementioning

confidence: 99%

A Medicinal Halophyte Ipomoea pes-caprae (Linn.) R. Br.: A Review of Its Botany, Traditional Uses, Phytochemistry, and Bioactivity

et al. 2022

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“…Albinosinic acids F (23) and G (24) had the same linear tretasaccharide core with the difference in the aglycone unit. Their oligosaccharide cores were composed of one D-quinose, one D-glucose, one L-rhamnoses, and one D-fucose units.…”

Section: Albinosinic Acids D-imentioning

confidence: 99%

“…Up to now, a number of reviews have summarized studies on the chemical constituents, biological activity, or synthesis aspects of resin glycosides from family Convolvulaceae 9,10,19–27 . In 2010, professor Pereda‐Miranda et al have given an excellent review about the structures, isolation, elucidation, synthesis, and significance of resin glycosides identified till the early stage of 2009 9 .…”

Section: Introductionmentioning

confidence: 99%

“…Since then, a number of new natural resin glycosides and derivatives have been isolated, some of which possessed new structural features or exhibited extraordinary bioactivities. During this period, several reviews have been published introducing the chemistry and biological activities of resin glycosides 10,23–27 ; however, none of them are comprehensive. Rodriguez et al highlighted the cytotoxic and chemosensitizing properties of resin glycosides 10 .…”

Section: Introductionmentioning

confidence: 99%

“…Rodriguez et al highlighted the cytotoxic and chemosensitizing properties of resin glycosides 10 . Lira‐Ricárdez and Pereda‐Miranda focused on the multidrug resistance reversal effects of resin glycosides in bacterial pathogens and human cancer cells 23 . Ono only summarized their own studies on the resin glycosides from some Convolvulaceae plants 24 .…”

Section: Introductionmentioning

confidence: 99%

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Chemistry and biological activity of resin glycosides from Convolvulaceae species

Fan

Jiang

et al. 2022

Medicinal Research Reviews

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Carbohydrate-based drug discovery has gained more and more attention during the last few decades. Resin glycoside is a kind of novel and complex glycolipids mainly distributed in plants of the family Convolvulaceae. Over the last decade, a number of natural resin glycosides and derivatives have been isolated and identified, and exhibited a broad spectrum of biological activities, such as cytotoxic, multidrug-resistant reversal on both microbial pathogens and mammalian cancer cells, antivirus, anticonvulsant, antidepressant, sedative, vasorelaxant, laxative, and α-glucosidase inhibitory effects, indicating their potential as lead compounds for drug discovery. A systematic review of the literature studies was carried out to summarize the chemistry and biological activity of resin glycosides from Convolvulaceae species, based on various data sources such as PubMed, Web of Science, Scopus, and Google scholar. The keyword "Convolvulaceae" was paired with "resin glycoside," "glycosidic acid," "glycolipid," or "oligosaccharide," and the references published between 2009 and June 2021 were covered. In this article, we comprehensively reviewed the structures of 288 natural resin glycoside and derivatives newly reported in the last decade. Moreover, we summarized the biological activities and mechanisms of action of the resin

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Identification of α-Glucosidase Inhibitors from Ipomoea alba by Affinity-Directed Fractionation-Mass Spectrometry

Rosas-Ramírez

Pereda‐Miranda

Escandón-Rivera

et al. 2020

Rev. Bras. Farmacogn.

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Reversal of multidrug resistance by amphiphilic morning glory resin glycosides in bacterial pathogens and human cancer cells

Cited by 17 publications

References 95 publications

A Medicinal Halophyte Ipomoea pes-caprae (Linn.) R. Br.: A Review of Its Botany, Traditional Uses, Phytochemistry, and Bioactivity

A Medicinal Halophyte Ipomoea pes-caprae (Linn.) R. Br.: A Review of Its Botany, Traditional Uses, Phytochemistry, and Bioactivity

Chemistry and biological activity of resin glycosides from Convolvulaceae species

Identification of α-Glucosidase Inhibitors from Ipomoea alba by Affinity-Directed Fractionation-Mass Spectrometry

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