Reversal of Lens Changes in Early Diabetes

Effect of Glycemic Control on Refractive Changes in Diabetic Patients With Hyperglycemia

“…It has been reported that hyperglycemia may lead to the development of myopia, while hypoglycemia may result in the development of hyperopia. [5][6][7] Although some investigators have shown mainly hyperopic changes after systemic treatment of hyperglycemia, [8][9][10][11] both hyperopic and myopic changes have also been observed in diabetic eyes in some other studies. [12][13][14] Those refractive changes observed during unstable blood sugar levels have been thought to be related to both morphologic and functional changes of the lens, [14][15][16] however, the underlying mechanism is still largely unknown.…”

Measuring the refractive properties of the diabetic eye during blurred vision and hyperglycaemia using aberrometry and Scheimpflug imaging

“…However, there seems to be no consensus in the literature on the direction and origin of these refractive changes. Myopic shifts (Duke-Elder 1925;Turtz & Turtz 1958;Birnbaum & Leu 1975;Gwinup & Villarreal 1976;Mantyjarvi 1988;Fledelius et al 1990;Furushima et al 1999), as well as hyperopic shifts (Huggert 1954;Planten 1975;Planten et al 1978;Varma et al 1980;Eva et al 1982;Kluxen & Scholz 1987;Imai & Matsuda 1992;Saito et al 1993;Okamoto et al 2000;Giusti 2003;Herse 2005;Sonmez et al 2005;Tai et al 2006) have often been reported in patients with severe acute hyperglycaemia, or during intensive treatment of acute metabolic dysregulation. Duke-Elder (1925) described a myopic shift in hyperglycaemia and a hyperopic shift after a rapid decrease Measuring the refractive properties of the diabetic eye during blurred vision and hyperglycaemia using aberrometry and Scheimpflug imaging in blood glucose levels.…”

Damage to the Crystalline Lens in Infants of Diabetic Mothers: A Pathology So Far Neglected?

“…The cutting of the umbilical cord shuts off the supply of maternal glucose, and the glycemia rapidly di minishes, while it is known that the degener ative process in the crystalline lens of diabet ics. in the early stages, can regress if the high glucose environment is removed or signifi cantly reduced [11,12]. On the contrary, in pups of diabetic rats, serious dysmctabolic conditions persist because of lesions sustained by the B cells during the fetal period [13], and the cataract may continue to evolve, as we have seen, even after birth.…”