Reversal of atherosclerosis by restoration of vascular copper homeostasis
Xiao Zuo,
Xueqin Ding,
Yaya Zhang
et al.
Abstract:Atherosclerosis has traditionally been considered as a disorder characterized by the accumulation of cholesterol and thrombotic materials within the arterial wall. However, it is now understood to be a complex inflammatory disease involving multiple factors. Central to the pathogenesis of atherosclerosis are the interactions among monocytes, macrophages, and neutrophils, which play pivotal roles in the initiation, progression, and destabilization of atherosclerotic lesions. Recent advances in our understanding… Show more
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