Reuse of a Previously Transplanted Kidney From a Deceased Donor Using Luminex Virtual Crossmatching: A Case Report

Park, S.J.; Oh, Se Hui; Kang, Mi Seon; Kim, T.H.; Kang, Sun Woo; Yoon, Young Chul; Kim, Y.H.

doi:10.1016/j.transproceed.2014.06.015

Cited by 10 publications

(9 citation statements)

References 11 publications

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“…From a medical perspective, the act of returning an organ that has once been donated (hereafter, organ restitution) is not permissible if serious safety issues arise due to returning the organ. Accumulating cases have reported on the reuse of transplanted kidneys 4–11. The anecdotal success of this procedure does not suggest it could routinely be accomplished safely.…”

Section: Discussionmentioning

confidence: 99%

Will you give my kidney back? Organ restitution in living-related kidney transplantation: ethical analyses

et al. 2019

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In this article, we perform a thought experiment about living donor kidney transplantation. If a living kidney donor becomes in need of renal replacement treatment due to dysfunction of the remaining kidney after donation, can the donor ask the recipient to give back the kidney that had been donated? We call this problem organ restitution and discussed it from the ethical viewpoint. Living organ transplantation is a kind of ‘designated donation’ and subsequently has a contract-like character. First, assuming a case in which original donor (A) wishes the return of the organ which had been transplanted into B, and the original recipient (B) agrees, organ restitution will be permissible based on contract-like agreement. However, careful and detailed consideration is necessary to determine whether this leaves no room to question the authenticity of B’s consent. Second, if B offers to give back the organ to A, then B’s act is a supererogatory act, and is praiseworthy and meritorious. Such an offer is a matter of virtue, not obligation. Third, if A wishes B to return the organ, but B does not wish/allow this to happen, it is likely difficult to justify returning the organ to A by violating B’s right to bodily integrity. But B’s refusal to return the donated organ cannot be deemed praiseworthy, because B forgets the great kindness once received from A. Rather than calling this an obligation, we encourage B to consider such virtuous conduct.

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Section: Discussionmentioning

confidence: 99%

Will you give my kidney back? Organ restitution in living-related kidney transplantation: ethical analyses

et al. 2019

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“…In kidney transplantation, repeated transplantation of a graft has been described previously. 1,2 To our knowledge, repeated donation of a previously transplanted lung has not been reported before.…”

Section: Introductionmentioning

confidence: 90%

Single lung transplantation from a donor 8 months after double lung transplantation

Bobylev

Salman

Sommer

et al. 2018

American Journal of Transplantation

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“…Only a few cases of transplanting a previously transplanted kidney are published. [17][18][19][20][21]25,[28][29][30] Furthermore, long-term implications of such a retransplantation are not well known. In some reports there were only short-term outcomes described until 1 year posttransplant, 20,25,30 some reports had a follow up of 1-4 years.…”

Section: Casementioning

confidence: 99%

“…[17][18][19][20][21]25,[28][29][30] Furthermore, long-term implications of such a retransplantation are not well known. In some reports there were only short-term outcomes described until 1 year posttransplant, 20,25,30 some reports had a follow up of 1-4 years. 18,19,28 Two case reports showed a successful reuse of a transplanted kidney with a follow-up of 5 years 21 and 12 years, 29 respectively, and all published cases had a good graft function in their follow-up time.…”

Section: Casementioning

confidence: 99%

“…Another option is the transplantation of a previously transplanted kidney when a deceased donor presents a well-functioning renal allograft. [16][17][18][19][20][21] This option is hardly used at the moment, but might be a possibility to expand the pool of donors. The question is whether this procedure may be a safe option in times of organ shortage or whether special prerequisites such as good renal function without an extended time frame since the previous transplantation should be fulfilled for successful retransplantation of a previously transplanted kidney.…”

Section: Introductionmentioning

confidence: 99%

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Retransplanting a previously transplanted kidney: A safe strategy in times of organ shortage?

Karakizlis

Rosmalen

Boide

et al. 2021

Clinical Transplantation

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Background:The shortage of organs for transplantation remains a global problem. The retransplantation of a previously transplanted kidney might be a possibility to expand the pool of donors. We provide our experience with the successful reuse of transplanted kidneys in the Eurotransplant region.Methods: A query in the Eurotransplant database was performed between January 1, 1995 and December 31, 2015, to find kidney donors who themselves had previously received a kidney graft.Results: Nine out of a total of 68,554 allocated kidneys had previously been transplanted. Four of these kidneys were transplanted once again. The mean interval between the first transplant and retransplantation was 1689±1682 days (SD; range 55-5,333 days). At the time of the first transplantation the mean serum creatinine of the donors was 1.0 mg/dl (.6-1.3 mg/dl) and at the second transplantation 1.4 mg/dl (.8-1.5 mg/dl). The mean graft survival in the first recipient was 50 months (2-110 months) and in the second recipient 111 months (40-215 months). Conclusion:Transplantation of a previously transplanted kidney may successfully be performed with well-preserved graft function and long-term graft survival, even if the first transplantation was performed a long time ago. Such organs should be considered even for younger recipients in carefully selected cases.

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Reuse of a Previously Transplanted Kidney From a Deceased Donor Using Luminex Virtual Crossmatching: A Case Report

Cited by 10 publications

References 11 publications

Will you give my kidney back? Organ restitution in living-related kidney transplantation: ethical analyses

Will you give my kidney back? Organ restitution in living-related kidney transplantation: ethical analyses

Single lung transplantation from a donor 8 months after double lung transplantation

Retransplanting a previously transplanted kidney: A safe strategy in times of organ shortage?

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