Retrospective study of pulmonary and extrapulmonary tuberculosis cases in Giza Governorate during the period of 2014–2018

Abstract

Background Tuberculosis in Egypt is a main public health problem. Egypt is categorized among the mid-level incidence countries. The objective of this work is to study the epidemiology of TB in Giza Governorate during the period from 2014 to 2018. Results This study revealed that the total number of TB cases in Giza Governorate during the period from 2014 to 2018 was 3357 (2035 males and 1322 females including 199 children) with the highest number of cases in 2017 (n=770 cases). The highest incidence occurred in the age group 18–65 years (86.3%%, 78.8%, 83.8%, 84.2%, and 87.1%) and male gender (56.8%, 62.8%, 59.9%, 61.3%, and 61.5%) during the study period, respectively, and in urban residence, the higher percentage occurred in PTB than EPTB in 2014, 2015, 2016, and 2018 (66.2%, 58.9%, 57.3%, and 55.5%), respectively, while the incidence of the extra PTB was higher than PTB in 2017 (51.6% versus 48.4%). The increased incidence of new cases (92.9%, 89.6%, 92.7%, 91.8%, and 92.9%) during the 5 studied years are smear-positive and cure outcome (86.3%, 87.7%, 88.7%, 83.4%, and 83.4%, respectively) Conclusion Young, middle-aged male, and new smear-positive cases were highest in percentage. The highest percentage of PTB (66.2%) was registered in 2014, and the highest percentage of EPTB (51.6%) was registered in 2017. The increased percentage of cure outcome was during the period from 2014 to 2018 in Giza Governorate.

The clinical and functional characteristics of bronchiectasis among tuberculosis patients in Upper Egypt: a single-center study

“…The mean age of those patients was 46.81 years with range between 30 and 62 years. In consistent with the current study, Malik et al (2021) stated that the majority of cases with TB occurred between 18 and 65 years [21]. Unlike Yang et al (2019) who reported that bronchiectasis was more prevalent at the age of 40 or older [22], it was found that age of those with bronchiectasis was insignificantly lower than those without bronchiectasis.…”

“…It was found that those patients had significantly younger age in comparison to those without DRTB (32.5 ± 1.73 vs. 47.52 ± 7.98 years; p< 0.001) and all of them had liver disease. This study had high percentage of DRTB in comparison to Abd El Malik et al (2021) [21] who found out 20/3357 (0.59%) patients had DRTB. Moreover, there was no statistical difference between DRTB prevalence in patients with and without bronchiectasis.…”

The association of IL-17A rs2275913 single nucleotide polymorphism with anti-tuberculous drug resistance in patients with pulmonary tuberculosis

“…Tuberculosis (TB) is still a global health problem especially in developing countries, where it results in a high morbidity and mortality [ 1 ]. The problem is exaggerated by the increasing prevalence of drug-resistant tuberculosis (DR-TB), in which the treatment is characterized by high cost, longer time, lower effectiveness, and more side effects [ 2 ].…”