Retrospective study of perforated peptic ulcer: a surgical emergency

Mathur, Praveen; Kumawat, J. L.; Joshi, C. P.; Parihar, Suman

doi:10.18203/2349-2902.isj20163979

Cited by 6 publications

(17 citation statements)

References 10 publications

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“…14 Simple closure with omental patch is the procedure of choice and is the most commonly employed surgical technique in most studies. 13 We observed wound infection to be the most common complication in our study similar to the observation by the study Lee et al 15 Follow-up endoscopy of our study group revealed healed ulcer in majority which is similar to the finding by Mansberger JA.…”

Section: Discussionsupporting

confidence: 92%

“…[8][9][10] H. pylori prevalence is 50-80% in PPU and studies support the use of H. pylori eradication treatment in the effective management of peptic ulcer disease. 11,12 Abdominal pain was the most frequent presentation of patients in our study similar to the observation by Mathur PN et al 13 Literature review supports the association between duration of perforation with post-operative outcome. 14 Simple closure with omental patch is the procedure of choice and is the most commonly employed surgical technique in most studies.…”

Section: Discussionsupporting

confidence: 90%

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Perforated peptic ulcer (PPU): a one year review in tertiary care hospital in Uttarakhand, India

Kumar¹,

Kumar²

2017

Int Surg J

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Background: Peptic ulcer perforation is a common surgical emergency. The perforation usually involves the anterior wall of duodenum (60%), although, it might occur in antrum (20%) and lesser curvature of stomach (20%). Conventional open surgery involving repair with omental patch remains the gold standard treatment. This study evaluates the patterns and demographic factors associated with this common surgical disease and the outcome analysis of surgery in our state.Methods: The study was undertaken for patients admitted in surgery department in a single unit who underwent open surgery for perforated peptic ulcer. A total of 78 patients were assessed between January 2016 to January 2017.Results: The study found PPU to be a male dominated disease in fifth decade and with significant association with smoking and alcohol consumption. First part of duodenum being the commonest location of PPU, the peritoneal contamination was directly associated with the duration of symptoms. Wound infection was the most frequent post-operative complication. Simple repair with omental patch remains an effective treatment modality.Conclusions: Perforated peptic ulcer disease commonly affects middle aged males especially due to association with alcohol intake. Simple closure with omental patch followed by H. pylori eradication is an effective treatment modality.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 90%

Perforated peptic ulcer (PPU): a one year review in tertiary care hospital in Uttarakhand, India

Kumar¹,

Kumar²

2017

Int Surg J

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“…The highest incidence of patients with perforated peptic ulcer was found in the age group of 36-40 years in the present study. This is in accordance with the studies conducted by Mathur et al, 6 Alegbeleye et al, 7 Thorsen et al, 8 and Svanes. 9…”

Section: Age Incidencesupporting

confidence: 93%

“…Results of the study by Mathur et al 6 also show an increase in the incidence of pyloro-duodenal perforation.…”

Section: Distribution Of Site Of Ulcer Perforationmentioning

confidence: 81%

A Prospective Clinicoendoscopic Follow-up Study in Young Patients with Peptic Ulcer Perforation at a Tertiary Institute in Central India

Jahagirdaar¹,

Bomanwar²,

Joshi³

2017

Euroasian Journal of Hepato-Gastroenterology

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Background: Perforation peritonitis is one of the commonest encountered emergencies in the surgery casualty. This study was conducted with the aim of identifying risk factors in peptic ulcer disease (PUD) in young patients. Materials and methods: Seventy patients were evaluated in this study and were followed up with clinical examination and endoscopy at 8 weeks and 6 months. Results: Out of the total 70 patients, there was a mortality of 5 patients and 7 patients were lost to follow-up. Out of the remaining 57 patients, 56 were men and 1 was a woman. Maximum patients were from the age group of 35-40 years. The patients were categorized on the basis of their clinical symptoms and endoscopy results at the follow-up of 6 months in 4 categories-21 patients having an active ulcer and symptomatic, 15 patients having active ulcer but no symptoms, 16 patients who were asymptomatic and without an active ulcer and 5 patients nonulcer dyspepsia. Conclusion: Postoperative treatment with H 2 blockers or proton pump inhibiters along with anti-Helicobacter pylori regimen should be prescribed for all patients with peptic ulcer perforation. Routine endoscopic examination of such patients should also form a part of the follow-up to look for ulcer healing postoperatively.

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“…Typically patients with PPU were males with peak age between 40 to 60 years with low socioeconomic status this explains the presence of physiological stress, smoking, and alcohol abuse (21-26) is more common which leads to PUD. Tobacco chewing and bidi smoking is a common habit in rural places (27). Alcohol consumption causes gastric mucosal damage, stimulate acid secretion and increases serum gastrin level (28).…”

Section: Discussionmentioning

confidence: 99%

A Retrospective Comparative Study of Outcomes in Patients of Perforated Peptic Ulcer Applied With Cellan-Jones Repair Versus Graham's Patch

Choudhari¹,

Aslam²,

Siddiq³

2018

EJMR

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Perforated Peptic ulcer is a complication of peptic ulcer disease (PUD) and is a surgical emergency with high morbidity and mortality. This study was undertaken to compare the outcome in patients treated with Cellan-Jones repair and Grahams patch for the perforation of peptic ulcer (PPU). It is a retrospective study done on 50 patients operated for perforated peptic ulcer in the District Hospital at Al Ameen Medical College Hospital Bijapur Karnataka from 2002 to 2005. Patients with acute and chronic peptic ulcer perforation selected for surgery, out of 50 patients 38 patients selected for Cellan-Jones repair and 12 patients selected for Graham's patch. Statistical analysis using Chi-square test was used to study the outcome in patients treated with two different surgical procedures for that particular age, sex, and occupation. Age related morbidity and mortality was also compared in the given study. A total of 50 patients with perforated peptic ulcer 38 patient treated with Cellan-Jones repair and 12 patients applied with Graham's patch. The overall mortality rate is 6% with p-value ˂0/05; 95% C.I. This study shows that the patients treated with Cellan-Jones repair and Graham's patch for the perforated peptic ulcer is having almost same result. This indicates that both the surgical methods have better survival outcome.

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Retrospective study of perforated peptic ulcer: a surgical emergency

Cited by 6 publications

References 10 publications

Perforated peptic ulcer (PPU): a one year review in tertiary care hospital in Uttarakhand, India

Perforated peptic ulcer (PPU): a one year review in tertiary care hospital in Uttarakhand, India

A Prospective Clinicoendoscopic Follow-up Study in Young Patients with Peptic Ulcer Perforation at a Tertiary Institute in Central India

A Retrospective Comparative Study of Outcomes in Patients of Perforated Peptic Ulcer Applied With Cellan-Jones Repair Versus Graham's Patch

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