Retrospective study of papulonodular skin lesions and their clinopathological correlation

Patil, Rupali R.; Makdani, Mehul; Gunjalia, Asha P; Gandhi, Karan; Patel, Harshid L

doi:10.5455/ijmsph.2015.20112014123

Cited by 4 publications

(6 citation statements)

References 25 publications

(37 reference statements)

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“…In all cases, the tuberculin test was strongly positive, which is in agreement with the fact that Lupus vulgaris occurs in immunocompetent individuals. 13,14 The presentation was that of a hyperpigmented plaque with central scarring and atrophy over the right hand, similar to the common presentation described in previous studies. 8,13,14 We could not find any case reports of HIV coexisting with cutaneous TB.…”

Section: Cutaneous Tuberculosissupporting

confidence: 75%

“…Similar results are reported in previous studies. 12,13 Special stains (slit skin smear and Fite-Faraco) showed more consistent results in the lepromatous pole of the disease (Leprosy). Hence their utility is limited in the diagnosis and management of leprosyas their sensitivity was 44.8% for SSS and 28.5% for Fite-Faraco staining which is correlated with the other studies.…”

Section: Leprosymentioning

confidence: 89%

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A Histopathological Spectrum of Granulomatous Skin Lesions in a Tertiary Health Centre in Western Maharashtra

Jambekar,

Maindad,

Kharolkar

et al. 2023

J For Med Sci Law

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Section: Cutaneous Tuberculosissupporting

confidence: 75%

Section: Leprosymentioning

confidence: 89%

A Histopathological Spectrum of Granulomatous Skin Lesions in a Tertiary Health Centre in Western Maharashtra

Jambekar,

Maindad,

Kharolkar

et al. 2023

J For Med Sci Law

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“…However the study of Bezbaruah R and Baruah M, and Abubaker SD et al, neoplastic lesions were the major entites of the total cases studied[16,17].On comparing the overall correlation between the clinical and histopathological diagnosis of all the papulonodular lesions we recorded 79% of cases histopathological diagnosis was consistent with the clinical diagnosis. Other studies done byPatil R et al, and Gupta P et al, recorded a overall concordance of (89.33%) of 75 cases and 85% of 282 casaes, variation noted between the studies may be due to the difference in nature of lesions encountered in the study period[7,8] as shown in.…”

mentioning

confidence: 66%

“…Papulonodular lesions of the skin are the most commonly encountered lesions and usually manifests in a variety as infectious diseases, benign and malignant lesions, and also as metastatic tumours. So a brief history of the clinical findings, regarding age, sex, and various sites of lesions are important for aiding accurate diagnosis [7].…”

Section: Discussionmentioning

confidence: 99%

A Clinico-pathological Study of Papulonodular Lesions of Skin in a Rural Hospital Setup

Rubina¹,

Parthibhan²,

Sujitha³

et al. 2022

NJLM

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Introduction: Skin disorders are a common cause of morbidity in our country, High prevelance of dermatological lesions is seen in tropical countries. The spectrum of lesions varies significantly depending on the geographical region, so accurate diagnosis is of utmost importance as treatment is varied for different skin disorders presenting with similar clinical findings. Aim: To study the spectrum of papulonodular lesions of skin and to evaluate concordance between the clinical and histopathological diagnosis of papulonodular skin lesions. Materials and Methods: This prospective cross-sectional study was conducted in Department of Pathology at MVJ Medical College and Research Hospital, Hoskote, Karnataka, India, from October 2017 to September 2019. The study included 100 skin biopsies that had clinically presented as papules, nodules and as papulonodular lesions. Based on the histopathological findings the lesions were grouped according to aetiology and the final histopathological diagnosis was compared with the clinical diagnosis offered. The slides were stained with Haematoxylin and Eosin, examined under a microscope and findings were noted. Special stains on the tissue sections like Zeihl-Neelson and Fite Faraco were used when required. The qualitative characteristics presented using frequency and percentages, quantitative variables presented using Mean±SD. Results: In the 100 biopsies studied 77 cases were papular, 20 cases were nodular and 3 cases were both papular and nodular. The lesions were common in males (54%) with 67% being in the 21-50 years age group. Lesions were categorised into five aetiological groups based on histology i.e, non infectious papulosquamous (25%), eczematous (23%, Inflammatory (20%), Infectious (11%) and lastly neoplastic (21%). A clinico- pathological association of 79% was observed with differences mainly observed in the eczematous group and tumours. Conclusion: This study highlights the various common skin disorders that can present as papulonodular lesions and the significance of histopathological examination and clinico- pathological association for early diagnosis and management of skin lesions.

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“…Clinical history, age, sex and various sites of the lesion is important. 2 Cytology and skin biopsy form the basis of differential diagnosis in clinically similar nodular lesions thereby yielding important information to the pathologist and dermatologist. 3 Skin biopsy is preferred over Fine needle aspiration cytology (FNAC) due to their access for excision.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic utility of fine needle aspiration cytology in the evaluation of neoplastic cutaneous nodular lesions: experience from tertiary care institute

Soni

Mardi

2020

Int J Res Med Sci

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Background: Cutaneous nodules can result from neoplastic and non-neoplastic causes. The present study conducted with the aim to find out sensitivity, specificity and diagnostic accuracy of cytology in neoplastic cutaneous nodules.Methods: This prospective study was conducted for a period of one year from August 2017 to August 2018. Nodular skin lesions diagnosed clinically as neoplastic were assessed by Fine needle aspiration cytology (FNAC) and correlated with histopathology. The sensitivity, specificity and accuracy of FNAC were determined using histopathology as a gold standard.Results: 82 cases with nodular skin lesions were subjected to cytological examination and biopsy. Aspiration was inadequate in 03 cases. For diagnosing neoplastic lesions, FNAC had a sensitivity of 98.7%, specificity of 94.6% and diagnostic accuracy of 97.4%.Conclusion: FNAC is safe, rapid, cost effective, highly sensitive and specific for the diagnosis of neoplastic nodular skin lesions with high diagnostic accuracy.

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Retrospective study of papulonodular skin lesions and their clinopathological correlation

Cited by 4 publications

References 25 publications

A Histopathological Spectrum of Granulomatous Skin Lesions in a Tertiary Health Centre in Western Maharashtra

A Histopathological Spectrum of Granulomatous Skin Lesions in a Tertiary Health Centre in Western Maharashtra

A Clinico-pathological Study of Papulonodular Lesions of Skin in a Rural Hospital Setup

Diagnostic utility of fine needle aspiration cytology in the evaluation of neoplastic cutaneous nodular lesions: experience from tertiary care institute

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