Retrospective Study of Factors Affecting Efficacy of Therapy with Dye Pulsed Light for Erythematotelangiectatic Rosacea

Abstract

Introduction: Dye pulsed light (DPL) was proven to be effective at treating erythematous and telangiectatic skin disorders. However, there are limited data on the efficacy of DPL treatment for erythematotelangiectatic rosacea (ETR), and researchers do not fully understand the factors that may affect the efficacy. Here, we performed a study to investigate the efficacy of DPL treatment for ETR and determine the factors affecting that efficacy. Methods: Sixty-five patients with ETR underwent three treatment sessions with DPL at 4-week intervals and were followed up at 4 weeks after the last treatment session. Skin type, sex, age, lesion site, severity of erythema and telangiectasia, VISIA percentile ranking, clinical photographs and red area images were recorded at baseline. The post-treatment erythematous and telangiectatic scores and VISIA percentile rankings were recorded, and the effects of different personal and clinical factors on the efficacy were statistically analysed. Results: The erythema and telangiectasia scores and VISIA percentile rankings showed significant improvement after the DPL procedures (p \ 0.01). With regard to erythema, treatment efficacy was not affected by any of the investigated variables, including pre-treatment erythema scores, skin type, pre-treatment VISIA percentile ranking, sex, age and lesion site (p [ 0.05). With regard to telangiectasia, the treatment efficacy was greater for mild telangiectasia than for severe telangiectasia (odds ratio = 4.14, p \ 0.05). There was no significant difference in treatment efficacy between the moderate and severe categories (odds ratio = 4.00, p [ 0.05). Conclusion: DPL is not the optimal procedure for treating severe telangiectasia in patients with ETR, whereas the efficacy of the treatment for erythema was not affected by the severity of the condition.

Effectiveness and safety of a narrow band spectrum intense pulsed‐light dye with long pulse Nd:YAG laser for treating facial vascular lesions

“…This device uses a series of three filters, concentrating the light into a narrow and specific spectrum, allowing the treatment of a wide range of vascular lesions with a specific spectrum and pulse duration. The NB‐Dye‐VL module has been shown to be effective in treating port‐wine stains 14 and telangiectasias 27,28 . In our study, the NB‐Dye‐VL was used to treat three patients, one with telangiectasias and two with rosacea.…”

“…The NB-Dye-VL module has been shown to be effective in treating port-wine stains 14 and telangiectasias. 27,28 In our study, the NB-Dye-VL was used to treat three patients, one with telangiectasias and two with rosacea. In all three cases, the aesthetic outcomes achieved were excellent, with a weighted LSS of 5 in all cases, supporting previous findings.…”

Lasers in dermatology. Recommendations of the Polish Dermatological Society. Part II. Treatment of vascular lesions

“…Diffuse erythema and telangiectasias in the course of rosacea are effectively treated with lasers with a wavelength of 532 nm, 595 nm and generators of intense light pulses using appropriate 560 nm filters [39][40][41][42][43][44][45]. Lower filters for IPL are only possible for selected devices using in-built cooling and for patients with fair skin to avoid skin burns.…”

“…Rozlany rumień i teleangiektazje w przebiegu trądziku różowatego efektywnie poddają się terapii laserami o długości fal 532 nm, 595 nm oraz generatorami intensywnych pulsów światła przy zastosowaniu odpowiednich filtrów 560 nm [39][40][41][42][43][44][45]. Niższe filtry dla IPL są możliwe jedynie dla wybranych urządzeń przy zastosowaniu wbudowanego chłodzenia (aby nie doszło do poparzenia naskórka) i u pacjentów z niskimi fototypami.…”